552 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 127 funds opening new positions, 188 increasing their positions, 195 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

7% less call options, than puts

Call options by funds: $610M | Put options by funds: $657M

15.76% less ownership

Funds ownership: 115.5%99.74% (-16%)

27% less funds holding in top 10

Funds holding in top 10: 3324 (-9)

Holders
552
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
24
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$610M
Puts
$657M
Net Calls
Net Calls Change

Top Buyers

1 +$1.07B
2 +$589M
3 +$330M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$322M
5
OAG
Orbis Allan Gray
Bermuda
+$249M
Name Holding Trade Value Shares
Change
Change in
Stake
Assenagon Asset Management
126
Assenagon Asset Management
Luxembourg
$18.6M
Los Angeles Capital Management
127
Los Angeles Capital Management
California
$18.4M
WP
128
Woodline Partners
California
$18.2M
Barclays
129
Barclays
United Kingdom
$16.4M
JFG
130
Jefferies Financial Group
New York
$15.6M
AI
131
Axiom Investors
Connecticut
$15.5M
LPL Financial
132
LPL Financial
California
$15.4M
VanEck Associates
133
VanEck Associates
New York
$15.4M
SI
134
Sofinnova Investments
California
$15M
DCM
135
Driehaus Capital Management
Illinois
$14.3M
ACM
136
Atika Capital Management
New York
$13.7M
FAM
137
Fred Alger Management
New York
$13.5M
LP
138
LMR Partners
United Kingdom
$13.5M
RA
139
Royce & Associates
New York
$13.3M
Bank of Montreal
140
Bank of Montreal
Ontario, Canada
$13.2M
EAM
141
EULAV Asset Management
Florida
$13M
EIM
142
Essex Investment Management
Massachusetts
$12.5M
Man Group
143
Man Group
United Kingdom
$12.3M
Treasurer of the State of North Carolina
144
Treasurer of the State of North Carolina
North Carolina
$12.1M
PFSRSONJ
145
Police & Firemen's Retirement System of New Jersey
New Jersey
$11.9M
Citigroup
146
Citigroup
New York
$11.5M
RHJA
147
Rice Hall James & Associates
California
$11.5M
TI
148
Trexquant Investment
Connecticut
$11.1M
American Century Companies
149
American Century Companies
Missouri
$11M
ACM
150
Aquatic Capital Management
Illinois
$11M