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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Barclays
126
Barclays
United Kingdom
$19M -$6.91M -90,406 -32%
Victory Capital Management
127
Victory Capital Management
Texas
$18.4M -$17.3M -226,341 -55%
JF
128
Jump Financial
Illinois
$18.3M +$13.9M +181,554 New
RPAM
129
Rhenman & Partners Asset Management
Sweden
$17.7M -$770K -10,065 -5%
California State Teachers Retirement System (CalSTRS)
130
California State Teachers Retirement System (CalSTRS)
California
$17.5M +$1.21M +15,831 +10%
IC
131
Ikarian Capital
Texas
$16.5M +$6.04M +78,951 +93%
Prudential Financial
132
Prudential Financial
New Jersey
$15.6M +$20.1K +263 +0.2%
BGI
133
B Group Inc
Texas
$15.6M -$8.22M -107,500 -41%
WCM Investment Management
134
WCM Investment Management
California
$15.3M +$735K +9,607 +7%
PAM
135
Panagora Asset Management
Massachusetts
$15.1M -$12M -157,126 -51%
FCM
136
Frontier Capital Management
Massachusetts
$14.9M -$31.3M -409,786 -73%
Tudor Investment Corp
137
Tudor Investment Corp
Connecticut
$13.5M +$10.2M +134,010 New
State Board of Administration of Florida Retirement System
138
State Board of Administration of Florida Retirement System
Florida
$13.1M +$7.08M +92,533 +246%
JG
139
Jain Global
New York
$12.8M +$9.72M +127,161 New
VanEck Associates
140
VanEck Associates
New York
$12.1M -$288K -3,766 -3%
SBH
141
Segall Bryant & Hamill
Illinois
$12M -$3.95M -51,723 -30%
State of Wisconsin Investment Board
142
State of Wisconsin Investment Board
Wisconsin
$11.9M -$613K -8,014 -6%
GIM
143
Granahan Investment Management
Massachusetts
$11.7M -$5.5M -71,885 -38%
Federated Hermes
144
Federated Hermes
Pennsylvania
$10.9M -$6.44M -84,258 -44%
DCM
145
Driehaus Capital Management
Illinois
$10.9M -$17.1M -223,378 -67%
Rafferty Asset Management
146
Rafferty Asset Management
New York
$9.87M -$3.66M -47,874 -33%
QC
147
Quadrature Capital
United Kingdom
$9.73M +$6.82M +89,217 +1,192%
RAM
148
Readystate Asset Management
Illinois
$9.47M -$3.1M -40,517 -30%
Verition Fund Management
149
Verition Fund Management
Connecticut
$9.4M +$5.11M +66,896 +253%
ECM
150
ExodusPoint Capital Management
New York
$9.33M +$377K +4,934 +6%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.