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663 hedge funds and large institutions have $23.8B invested in Insmed in 2026 Q2 according to their latest regulatory filings, with 119 funds opening new positions, 244 increasing their positions, 230 reducing their positions, and 121 closing their positions.

New
Increased
Maintained
Reduced
Closed

49% more call options, than puts

Call options by funds: $614M | Put options by funds: $411M

6% more repeat investments, than reductions

Existing positions increased: 244 | Existing positions reduced: 230

0.53% more ownership

Funds ownership: 102.5%103.03% (+0.53%)

2% less first-time investments, than exits

New positions opened: 119 | Existing positions closed: 121

1% less funds holding

Funds holding: 673663 (-10)

33% less capital invested

Capital invested by funds: $35.7B → $23.8B (-$11.9B)

38% less funds holding in top 10

Funds holding in top 10: 2616 (-10)

Holders
663
Holders Change
-10
Holders Change %
-1.49%
% of All Funds
8.01%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.19%
New
119
Increased
244
Reduced
230
Closed
121
Calls
$614M
Puts
$411M
Net Calls
+$202M
Net Calls Change
+$81.9M
Name Holding Trade Value Shares
Change
Change in
Stake
DCM
101
Defilade Capital Management
California
$30M +$10.5M +86,929 +45%
HSBC Holdings
102
HSBC Holdings
United Kingdom
$29.9M +$19.8M +163,505 +140%
RhumbLine Advisers
103
RhumbLine Advisers
Massachusetts
$29.1M +$12.1K +100 +0%
FTM
104
First Turn Management
California
$28.1M +$1.86M +15,376 +6%
CWG
105
C WorldWide Group
Denmark
$27.8M +$12.1M +100,000 +62%
Wells Fargo
106
Wells Fargo
California
$27.7M -$40.9M -337,532 -57%
California Public Employees Retirement System
107
California Public Employees Retirement System
California
$26.7M -$11.4M -94,262 -27%
VPC
108
Vestal Point Capital
New York
$26.7M +$30.3M +250,000 New
TD Asset Management
109
TD Asset Management
Ontario, Canada
$25.6M +$9.29M +76,758 +47%
CM
110
Caption Management
Oklahoma
$25.2M +$28.6M +236,000 New
TECP
111
Trails Edge Capital Partners
Georgia
$24.6M +$27.9M +230,331 New
ACM
112
ADAR1 Capital Management
Texas
$24.4M +$23.4M +193,128 +546%
NAMI
113
Nomura Asset Management International
Pennsylvania
$23.4M -$112M -924,616 -81%
Assenagon Asset Management
114
Assenagon Asset Management
Luxembourg
$23.3M +$18.8M +155,011 +245%
DnB Asset Management
115
DnB Asset Management
Norway
$22.7M +$19.4M +160,089 +301%
Connor, Clark & Lunn Investment Management (CC&L)
116
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$22.7M +$20.2M +166,446 +360%
LP
117
Longaeva Partners
Illinois
$21.5M +$24.4M +201,226 New
UIM
118
USS Investment Management
United Kingdom
$20.9M +$23.8M +196,253 New
Tudor Investment Corp
119
Tudor Investment Corp
Connecticut
$20.8M +$23.7M +195,391 New
Jane Street
120
Jane Street
New York
$20.6M +$22.1M +182,127 +1,597%
Holocene Advisors
121
Holocene Advisors
New York
$20.6M +$23.4M +192,879 New
Alyeska Investment Group
122
Alyeska Investment Group
Illinois
$20.3M +$17.2M +142,142 +295%
Handelsbanken Fonder
123
Handelsbanken Fonder
Sweden
$20.2M +$14.8M +122,100 +181%
Barclays
124
Barclays
United Kingdom
$19.8M -$10.9M -90,088 -33%
State Board of Administration of Florida Retirement System
125
State Board of Administration of Florida Retirement System
Florida
$19.3M +$95.5K +789 +0.4%

INSM Hedge Fund Activity: Q2 2026 in Review

663 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2026, worth a combined $23.8B — down 33% from $35.7B a quarter earlier.

Sellers outnumbered buyers: 121 funds closed out of INSM and 119 opened new positions — a net loss of 2 holders — while 230 trimmed existing stakes and 244 added.

The largest buyer was Orbis Allan Gray, adding an estimated $509M. The largest seller was JP Morgan Chase, cutting an estimated $1.66B.

  • 663 institutional investors held Insmed (INSM) as of Q2 2026, down from 673 in Q1 2026.
  • Funds reported $23.8B of Insmed stock for Q2 2026, down 33% quarter-over-quarter.
  • 119 funds opened new Insmed positions in Q2 2026 and 121 closed out, a net change of -2 holders.
  • The largest Insmed buyer in Q2 2026 was Orbis Allan Gray, an estimated $509M added.
  • The largest Insmed seller in Q2 2026 was JP Morgan Chase, an estimated $1.66B sold.

Based on aggregated 13F filings for Q2 2026.