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566 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 130 funds opening new positions, 194 increasing their positions, 197 reducing their positions, and 72 closing their positions.

New
Increased
Maintained
Reduced
Closed

81% more first-time investments, than exits

New positions opened: 130 | Existing positions closed: 72

43% more capital invested

Capital invested by funds: $21.2B → $30.3B (+$9.17B)

10% more funds holding

Funds holding: 516566 (+50)

2% less repeat investments, than reductions

Existing positions increased: 194 | Existing positions reduced: 197

7% less call options, than puts

Call options by funds: $610M | Put options by funds: $657M

15.75% less ownership

Funds ownership: 115.51%99.76% (-16%)

27% less funds holding in top 10

Funds holding in top 10: 3324 (-9)

Holders
566
Holders Change
+50
Holders Change %
+9.69%
% of All Funds
7.43%
Holding in Top 10
24
Holding in Top 10 Change
-9
Holding in Top 10 Change %
-27.27%
% of All Funds
0.32%
New
130
Increased
194
Reduced
197
Closed
72
Calls
$610M
Puts
$657M
Net Calls
-$47.7M
Net Calls Change
+$8.54M
Name Holding Trade Value Shares
Change
Change in
Stake
Allspring Global Investments
101
Allspring Global Investments
North Carolina
$33.5M -$9.39M -76,681 -25%
VOYA Investment Management
102
VOYA Investment Management
Georgia
$31.7M -$23M -187,840 -46%
SCM
103
Suvretta Capital Management
New York
$31.4M -$2.57M -21,000 -9%
RhumbLine Advisers
104
RhumbLine Advisers
Massachusetts
$30.7M +$558K +4,558 +2%
Legal & General Group
105
Legal & General Group
United Kingdom
$30M +$20.8K +170 +0.1%
SPS
106
Susquehanna Portfolio Strategies
Pennsylvania
$29.9M
SCM
107
Silverarc Capital Management
Massachusetts
$29.8M -$5.2M -42,412 -17%
Deutsche Bank
108
Deutsche Bank
Germany
$29.4M +$333K +2,719 +1%
NHAS
109
Novo Holdings A/S
Denmark
$28.8M -$58.8M -480,000 -71%
TCM
110
Tang Capital Management
California
$28.8M
NCM
111
Nearwater Capital Markets
Ireland
$28.8M +$24.5M +200,000 New
BNP Paribas Asset Management
112
BNP Paribas Asset Management
France
$28.6M -$12.7M -103,363 -34%
CWG
113
C WorldWide Group
Denmark
$28.2M -$9.19M -75,000 -28%
Manulife (Manufacturers Life Insurance)
114
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$27.9M -$3.97M -32,435 -14%
NIP
115
Nicholas Investment Partners
California
$26M -$1.83M -14,943 -8%
California State Teachers Retirement System (CalSTRS)
116
California State Teachers Retirement System (CalSTRS)
California
$25.8M +$719K +5,873 +3%
Russell Investments Group
117
Russell Investments Group
United Kingdom
$24M -$8.35M -68,158 -29%
Caisse de Depot et Placement du Quebec (CDPQ)
118
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$23.7M +$20.1M +164,400 New
Comerica Bank
119
Comerica Bank
Texas
$23.3M -$8.65M -70,595 -30%
AIM
120
AXA Investment Managers
France
$22.5M +$19.2M +156,431 New
Neuberger Berman Group
121
Neuberger Berman Group
New York
$21.6M +$17.1M +139,211 +1,278%
AG
122
Algert Global
California
$20.8M +$7.69M +62,802 +77%
State Board of Administration of Florida Retirement System
123
State Board of Administration of Florida Retirement System
Florida
$19.4M +$595K +4,855 +4%
State of Wisconsin Investment Board
124
State of Wisconsin Investment Board
Wisconsin
$19.2M +$1.89M +15,404 +13%
RPAM
125
Rhenman & Partners Asset Management
Sweden
$19M -$5.34M -43,550 -25%

INSM Hedge Fund Activity: Q3 2025 in Review

566 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q3 2025, worth a combined $30.3B — up 43% from $21.2B a quarter earlier.

Buyers outnumbered sellers: 130 funds opened new INSM positions and 72 closed out — a net gain of 58 holders — while 194 added to existing stakes and 197 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $908M. The largest seller was T. Rowe Price Associates, cutting an estimated $527M.

  • 566 institutional investors held Insmed (INSM) as of Q3 2025, up from 516 in Q2 2025.
  • Funds reported $30.3B of Insmed stock for Q3 2025, up 43% quarter-over-quarter.
  • 130 funds opened new Insmed positions in Q3 2025 and 72 closed out, a net change of +58 holders.
  • The largest Insmed buyer in Q3 2025 was JP Morgan Chase, an estimated $908M added.
  • The largest Insmed seller in Q3 2025 was T. Rowe Price Associates, an estimated $527M sold.

Based on aggregated 13F filings for Q3 2025.