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566 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 130 funds opening new positions, 194 increasing their positions, 197 reducing their positions, and 72 closing their positions.

New
Increased
Maintained
Reduced
Closed

81% more first-time investments, than exits

New positions opened: 130 | Existing positions closed: 72

43% more capital invested

Capital invested by funds: $21.2B → $30.3B (+$9.17B)

10% more funds holding

Funds holding: 516566 (+50)

2% less repeat investments, than reductions

Existing positions increased: 194 | Existing positions reduced: 197

7% less call options, than puts

Call options by funds: $610M | Put options by funds: $657M

15.75% less ownership

Funds ownership: 115.51%99.76% (-16%)

27% less funds holding in top 10

Funds holding in top 10: 3324 (-9)

Holders
566
Holders Change
+50
Holders Change %
+9.69%
% of All Funds
7.43%
Holding in Top 10
24
Holding in Top 10 Change
-9
Holding in Top 10 Change %
-27.27%
% of All Funds
0.32%
New
130
Increased
194
Reduced
197
Closed
72
Calls
$610M
Puts
$657M
Net Calls
-$47.7M
Net Calls Change
+$8.54M
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
76
TimesSquare Capital Management
New York
$61.2M -$54.9M -448,406 -51%
TD Asset Management
77
TD Asset Management
Ontario, Canada
$57.4M +$375K +3,062 +0.8%
CS
78
Candriam SCA
Luxembourg
$57.3M -$5.03M -41,100 -9%
Dimensional Fund Advisors
79
Dimensional Fund Advisors
Texas
$55.7M -$3.07M -25,073 -6%
RSCM
80
Rock Springs Capital Management
Maryland
$55.4M -$17.2M -140,000 -27%
IG
81
ING Group
Netherlands
$53.8M +$45.8M +373,500 New
PCH
82
Polar Capital Holdings
United Kingdom
$53.6M -$39.9M -326,073 -47%
Swiss National Bank
83
Swiss National Bank
Switzerland
$53.5M +$2.93M +23,900 +7%
Victory Capital Management
84
Victory Capital Management
Texas
$51.1M +$21.1M +172,134 +94%
Renaissance Technologies
85
Renaissance Technologies
New York
$50.8M +$5.41M +44,200 +14%
Amundi
86
Amundi
France
$50.2M +$37.4M +305,597 +2,658%
Envestnet Asset Management
87
Envestnet Asset Management
Illinois
$49.4M -$2.82M -23,042 -6%
LFCM
88
Long Focus Capital Management
Puerto Rico
$48.7M -$22.3M -182,200 -35%
FCM
89
Frontier Capital Management
Massachusetts
$47.4M +$22.2M +181,083 +123%
Federated Hermes
90
Federated Hermes
Pennsylvania
$47.3M +$26.9M +219,838 +203%
PSC
91
Patient Square Capital
California
$47M -$3.97M -32,400 -9%
FTM
92
First Turn Management
California
$46.1M -$6.48M -52,899 -14%
California Public Employees Retirement System
93
California Public Employees Retirement System
California
$44.8M +$10.9M +88,650 +40%
BHCM
94
Brevan Howard Capital Management
Jersey
$42.3M +$11.2M +91,453 +45%
SC
95
Samlyn Capital
New York
$42.1M +$35.9M +292,643 New
AQR Capital Management
96
AQR Capital Management
Connecticut
$40.9M +$29.1M +237,571 +478%
EHI
97
Eagle Health Investments
Connecticut
$39.1M -$19.2M -157,000 -37%
First Trust Advisors
98
First Trust Advisors
Illinois
$34.7M +$23.7M +193,254 +408%
Aberdeen Group
99
Aberdeen Group
United Kingdom
$33.8M -$9.2M -75,127 -24%
Susquehanna International Group
100
Susquehanna International Group
Pennsylvania
$33.6M +$2.56M +20,884 +10%

INSM Hedge Fund Activity: Q3 2025 in Review

566 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q3 2025, worth a combined $30.3B — up 43% from $21.2B a quarter earlier.

Buyers outnumbered sellers: 130 funds opened new INSM positions and 72 closed out — a net gain of 58 holders — while 194 added to existing stakes and 197 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $908M. The largest seller was T. Rowe Price Associates, cutting an estimated $527M.

  • 566 institutional investors held Insmed (INSM) as of Q3 2025, up from 516 in Q2 2025.
  • Funds reported $30.3B of Insmed stock for Q3 2025, up 43% quarter-over-quarter.
  • 130 funds opened new Insmed positions in Q3 2025 and 72 closed out, a net change of +58 holders.
  • The largest Insmed buyer in Q3 2025 was JP Morgan Chase, an estimated $908M added.
  • The largest Insmed seller in Q3 2025 was T. Rowe Price Associates, an estimated $527M sold.

Based on aggregated 13F filings for Q3 2025.