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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
PBA
76
Paradigm Biocapital Advisors
New York
$34.4M +$34.5M +451,359 New
NM
77
NWI Management
New York
$34.3M +$13.1M +171,000 +61%
Susquehanna International Group
78
Susquehanna International Group
Pennsylvania
$34.2M +$320K +4,179 +0.9%
EHI
79
Eagle Health Investments
Connecticut
$33.8M -$5.39M -70,400 -14%
MC
80
Maverick Capital
Texas
$32.4M +$32.5M +425,125 New
Allspring Global Investments
81
Allspring Global Investments
North Carolina
$31.6M +$1.19M +15,580 +4%
Victory Capital Management
82
Victory Capital Management
Texas
$31.2M -$112K -1,463 -0.4%
Raymond James Financial
83
Raymond James Financial
Florida
$31.2M +$3.48M +45,491 +13%
Two Sigma Investments
84
Two Sigma Investments
New York
$31M -$14.3M -187,093 -31%
FTM
85
First Turn Management
California
$30.6M -$3.47M -45,351 -10%
SEI Investments
86
SEI Investments
Pennsylvania
$30.2M +$2.55M +33,363 +9%
FAM
87
Fred Alger Management
New York
$28.9M -$545K -7,129 -2%
Citadel Advisors
88
Citadel Advisors
Florida
$28.6M +$3.91M +51,080 +16%
Dimensional Fund Advisors
89
Dimensional Fund Advisors
Texas
$28.4M +$1.61M +21,061 +6%
New York State Common Retirement Fund
90
New York State Common Retirement Fund
New York
$27.1M +$2.9M +37,969 +12%
EMFAT
91
Emerald Mutual Fund Advisers Trust
Pennsylvania
$27M -$3.58M -46,793 -12%
Aberdeen Group
92
Aberdeen Group
United Kingdom
$25.7M +$3.57M +46,704 +16%
DCM
93
Driehaus Capital Management
Illinois
$25.3M +$12.3M +160,170 +94%
PSC
94
Patient Square Capital
California
$25.2M +$1.77M +23,083 +8%
Swiss National Bank
95
Swiss National Bank
Switzerland
$25.1M +$627K +8,200 +3%
Envestnet Asset Management
96
Envestnet Asset Management
Illinois
$24.8M +$5.27M +68,949 +27%
SCM
97
Silverarc Capital Management
Massachusetts
$24.5M -$3.89M -50,864 -14%
CWG
98
C WorldWide Group
Denmark
$24.5M -$1.68M -22,000 -6%
Manulife (Manufacturers Life Insurance)
99
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$24.3M +$399K +5,211 +2%
AGP
100
Artia Global Partners
Florida
$24.3M +$11.5M +150,300 +89%

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.