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566 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 130 funds opening new positions, 194 increasing their positions, 197 reducing their positions, and 72 closing their positions.

New
Increased
Maintained
Reduced
Closed

81% more first-time investments, than exits

New positions opened: 130 | Existing positions closed: 72

43% more capital invested

Capital invested by funds: $21.2B → $30.3B (+$9.17B)

10% more funds holding

Funds holding: 516566 (+50)

2% less repeat investments, than reductions

Existing positions increased: 194 | Existing positions reduced: 197

7% less call options, than puts

Call options by funds: $610M | Put options by funds: $657M

15.75% less ownership

Funds ownership: 115.51%99.76% (-16%)

27% less funds holding in top 10

Funds holding in top 10: 3324 (-9)

Holders
566
Holders Change
+50
Holders Change %
+9.69%
% of All Funds
7.43%
Holding in Top 10
24
Holding in Top 10 Change
-9
Holding in Top 10 Change %
-27.27%
% of All Funds
0.32%
New
130
Increased
194
Reduced
197
Closed
72
Calls
$610M
Puts
$657M
Net Calls
-$47.7M
Net Calls Change
+$8.54M
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
51
Wellington Management Group
Massachusetts
$103M -$54.1M -441,656 -38%
PA
52
Perceptive Advisors
New York
$101M +$6.36M +51,878 +8%
Marshall Wace
53
Marshall Wace
United Kingdom
$94.9M -$55.7M -454,714 -41%
MC
54
Maverick Capital
Texas
$94.5M -$18.1M -147,594 -18%
Macquarie Group
55
Macquarie Group
Australia
$93.6M -$58.9M -481,076 -43%
Ensign Peak Advisors
56
Ensign Peak Advisors
Utah
$92.5M +$9.51M +77,645 +14%
Jennison Associates
57
Jennison Associates
New York
$86.8M -$13.8M -112,831 -16%
GKIM
58
GW&K Investment Management
Massachusetts
$86.7M -$82.4M -672,513 -53%
SEI Investments
59
SEI Investments
Pennsylvania
$85.5M +$19.6M +160,257 +37%
N
60
Nuveen
North Carolina
$84.7M -$106K -865 -0.1%
1832 Asset Management
61
1832 Asset Management
Ontario, Canada
$84.2M +$71.6M +584,800 New
Wells Fargo
62
Wells Fargo
California
$74M +$31.2M +254,642 +98%
UBS AM
63
UBS AM
Illinois
$73.8M -$22.4M -183,212 -26%
Bank of Nova Scotia
64
Bank of Nova Scotia
Ontario, Canada
$72.9M +$62M +506,245 New
Alkeon Capital Management
65
Alkeon Capital Management
New York
$72M
Loomis, Sayles & Company
66
Loomis, Sayles & Company
Massachusetts
$70.9M -$36.9M -301,273 -38%
PAI
67
Palo Alto Investors
California
$70.8M -$45.7M -373,308 -43%
Westfield Capital Management
68
Westfield Capital Management
Massachusetts
$70.3M -$104M -851,361 -64%
Voloridge Investment Management
69
Voloridge Investment Management
Florida
$67.9M +$19.4M +158,596 +51%
DM
70
Deerfield Management
New York
$67.8M -$28.1M -229,700 -33%
Point72 Asset Management
71
Point72 Asset Management
Connecticut
$66.9M -$3.24M -26,450 -5%
AAA
72
Affinity Asset Advisors
New York
$64.8M -$3.06M -25,000 -5%
New York State Common Retirement Fund
73
New York State Common Retirement Fund
New York
$64.2M +$2.22M +18,123 +4%
BNP Paribas Financial Markets
74
BNP Paribas Financial Markets
France
$62.4M -$39.3M -320,820 -43%
CAM
75
Cormorant Asset Management
Massachusetts
$61.9M -$13.5M -110,000 -20%

INSM Hedge Fund Activity: Q3 2025 in Review

566 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q3 2025, worth a combined $30.3B — up 43% from $21.2B a quarter earlier.

Buyers outnumbered sellers: 130 funds opened new INSM positions and 72 closed out — a net gain of 58 holders — while 194 added to existing stakes and 197 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $908M. The largest seller was T. Rowe Price Associates, cutting an estimated $527M.

  • 566 institutional investors held Insmed (INSM) as of Q3 2025, up from 516 in Q2 2025.
  • Funds reported $30.3B of Insmed stock for Q3 2025, up 43% quarter-over-quarter.
  • 130 funds opened new Insmed positions in Q3 2025 and 72 closed out, a net change of +58 holders.
  • The largest Insmed buyer in Q3 2025 was JP Morgan Chase, an estimated $908M added.
  • The largest Insmed seller in Q3 2025 was T. Rowe Price Associates, an estimated $527M sold.

Based on aggregated 13F filings for Q3 2025.