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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
51
D.E. Shaw & Co
New York
$56.1M +$17.3M +226,093 +44%
PCH
52
Polar Capital Holdings
United Kingdom
$55.6M -$95.2K -1,245 -0.2%
NHAS
53
Novo Holdings A/S
Denmark
$55.3M
SPPAM
54
Summit Partners Public Asset Management
Massachusetts
$53.7M +$5.01M +65,518 +10%
Marshall Wace
55
Marshall Wace
United Kingdom
$53.1M -$28.1M -367,978 -35%
TIM
56
Thornburg Investment Management
New Mexico
$52.5M -$452K -5,909 -8%
Millennium Management
57
Millennium Management
New York
$51.8M -$1.52M -19,815 -3%
Brown Advisory
58
Brown Advisory
Maryland
$51.3M +$723K +9,453 +1%
LFCM
59
Long Focus Capital Management
Puerto Rico
$48.1M -$1.53M -20,000 -3%
BNP Paribas Asset Management
60
BNP Paribas Asset Management
France
$46.8M -$3.18M -41,632 -6%
EA
61
Emerald Advisers
Pennsylvania
$45.3M -$6.93M -90,623 -13%
Ensign Peak Advisors
62
Ensign Peak Advisors
Utah
$45M +$4.62M +60,350 +11%
VOYA Investment Management
63
VOYA Investment Management
Georgia
$44.7M +$2.8M +36,561 +7%
Fiera Capital (Canada)
64
Fiera Capital (Canada)
Quebec, Canada
$44.2M -$200K -2,617 -0.4%
FCM
65
Frontier Capital Management
Massachusetts
$42.5M +$9.38M +122,581 +28%
UBS AM
66
UBS AM
Illinois
$41.2M +$4.03M +52,637 +11%
CAM
67
Cormorant Asset Management
Massachusetts
$40.1M -$9.56M -125,000 -19%
RSCM
68
Rock Springs Capital Management
Maryland
$39.4M -$2.61M -34,100 -6%
PA
69
Perceptive Advisors
New York
$38.9M +$27.9M +365,300 +254%
TD Asset Management
70
TD Asset Management
Ontario, Canada
$38.3M -$1.89M -24,658 -5%
1832 Asset Management
71
1832 Asset Management
Ontario, Canada
$37.2M +$37.3M +487,800 New
UBS Group
72
UBS Group
Switzerland
$36.4M +$5.5M +71,911 +18%
BNP Paribas Financial Markets
73
BNP Paribas Financial Markets
France
$35.2M +$21M +274,647 +147%
DM
74
Deerfield Management
New York
$34.9M +$35M +458,000 New
CS
75
Candriam SCA
Luxembourg
$34.7M +$144K +1,888 +0.4%

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.