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566 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 130 funds opening new positions, 194 increasing their positions, 197 reducing their positions, and 72 closing their positions.

New
Increased
Maintained
Reduced
Closed

81% more first-time investments, than exits

New positions opened: 130 | Existing positions closed: 72

43% more capital invested

Capital invested by funds: $21.2B → $30.3B (+$9.17B)

10% more funds holding

Funds holding: 516566 (+50)

2% less repeat investments, than reductions

Existing positions increased: 194 | Existing positions reduced: 197

7% less call options, than puts

Call options by funds: $610M | Put options by funds: $657M

15.75% less ownership

Funds ownership: 115.51%99.76% (-16%)

27% less funds holding in top 10

Funds holding in top 10: 3324 (-9)

Holders
566
Holders Change
+50
Holders Change %
+9.69%
% of All Funds
7.43%
Holding in Top 10
24
Holding in Top 10 Change
-9
Holding in Top 10 Change %
-27.27%
% of All Funds
0.32%
New
130
Increased
194
Reduced
197
Closed
72
Calls
$610M
Puts
$657M
Net Calls
-$47.7M
Net Calls Change
+$8.54M
Name Holding Trade Value Shares
Change
Change in
Stake
JF
576
Jump Financial
Illinois
-$18.3M -181,554 Closed
PAM
577
Panagora Asset Management
Massachusetts
-$15.1M -149,591 Closed
SBH
578
Segall Bryant & Hamill
Illinois
-$12M -119,136 Closed
RAM
579
Readystate Asset Management
Illinois
-$9.47M -94,052 Closed
ECM
580
ExodusPoint Capital Management
New York
-$9.33M -92,717 Closed
PAMP
581
Polar Asset Management Partners
Ontario, Canada
-$9.29M -92,300 Closed
PCM
582
Peregrine Capital Management
Minnesota
-$8.93M -88,695 Closed
Hudson Bay Capital Management
583
Hudson Bay Capital Management
Connecticut
-$8.23M -81,743 Closed
ITP
584
Iron Triangle Partners
Connecticut
-$7.04M -70,000 Closed
FLAM
585
First Light Asset Management
Minnesota
-$6.33M -62,901 Closed
XT
586
XTX Topco
Cayman Islands
-$5.67M -56,380 Closed
VF
587
Virtu Financial
New York
-$5.46M -54,302 Closed
EGI
588
EAM Global Investors
California
-$5.05M -50,206 Closed
ABG
589
Ally Bridge Group
New York
-$4.8M -47,710 Closed
HCA
590
Harbor Capital Advisors
Illinois
-$4.71M -46,786 Closed
MIM
591
Monashee Investment Management
Massachusetts
-$4.03M -40,000 Closed
NRD
592
Nebula Research & Development
New York
-$3.69M -36,661 Closed
ACH
593
ArrowMark Colorado Holdings
Colorado
-$3.02M -30,000 Closed
SRL
594
Scientech Research LLC
New Jersey
-$2.78M -27,642 Closed
CL
595
CSS LLC
Illinois
-$2.76M -27,375 Closed
RCAP
596
Resolute Capital Asset Partners
Colorado
-$2.75M -27,301 Closed
UOC
597
UBS O'Connor
Illinois
-$2.65M -26,301 Closed
WG
598
Winton Group
United Kingdom
-$2.24M -22,268 Closed
QT
599
Quantbot Technologies
New York
-$2.22M -22,067 Closed
BG
600
Bollard Group
Massachusetts
-$1.73M -17,191 Closed

INSM Hedge Fund Activity: Q3 2025 in Review

566 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q3 2025, worth a combined $30.3B — up 43% from $21.2B a quarter earlier.

Buyers outnumbered sellers: 130 funds opened new INSM positions and 72 closed out — a net gain of 58 holders — while 194 added to existing stakes and 197 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $908M. The largest seller was T. Rowe Price Associates, cutting an estimated $527M.

  • 566 institutional investors held Insmed (INSM) as of Q3 2025, up from 516 in Q2 2025.
  • Funds reported $30.3B of Insmed stock for Q3 2025, up 43% quarter-over-quarter.
  • 130 funds opened new Insmed positions in Q3 2025 and 72 closed out, a net change of +58 holders.
  • The largest Insmed buyer in Q3 2025 was JP Morgan Chase, an estimated $908M added.
  • The largest Insmed seller in Q3 2025 was T. Rowe Price Associates, an estimated $527M sold.

Based on aggregated 13F filings for Q3 2025.