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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
IIM
526
INTECH Investment Management
Florida
-$7.78M -101,979 Closed
TLP
527
Tri Locum Partners
New York
-$7.77M -101,859 Closed
ACM
528
Atika Capital Management
New York
-$7.32M -96,000 Closed
CF
529
Corebridge Financial
Texas
-$6.44M -84,466 Closed
CWM
530
CIBC World Markets
New York
-$2.92M -38,258 Closed
PHP
531
Parkman Healthcare Partners
Connecticut
-$2.89M -37,901 Closed
HWAM
532
Hennion & Walsh Asset Management
New Jersey
-$2.72M -35,704 Closed
SFAM
533
Springhill Fund Asset Management
Hong Kong
-$1.46M -19,192 Closed
AIP
534
Ameritas Investment Partners
Nebraska
-$1.34M -17,551 Closed
CP
535
CenterBook Partners
Connecticut
-$1.22M -15,991 Closed
Simplex Trading
536
Simplex Trading
Illinois
-$1.11M -14,467 Closed
TRSOTSOK
537
Teachers Retirement System of the State of Kentucky
Kentucky
-$975K -12,775 Closed
SP
538
SIH Partners
Delaware
-$871K -11,415 Closed
AI
539
Allostery Investments
Connecticut
-$763K -10,000 Closed
Group One Trading
540
Group One Trading
Illinois
-$563K -7,361 Closed
ACM
541
ADAR1 Capital Management
Texas
-$463K -6,074 Closed
CAU
542
Caxton Associates (UK)
-$441K -5,785 Closed
CF
543
Cantor Fitzgerald
New York
-$386K -5,060 Closed
SC
544
Syon Capital
California
-$376K -4,929 Closed
FAIM
545
Financial Advocates Investment Management
Washington
-$369K -4,836 Closed
CAM
546
Cresset Asset Management
Illinois
-$311K -4,083 Closed
EC
547
EntryPoint Capital
New York
-$305K -3,997 Closed
BBP
548
Banco BTG Pactual
Brazil
-$251K -3,285 Closed
IC
549
IEQ Capital
California
-$244K -3,202 Closed
TC
550
TownSquare Capital
Utah
-$236K -3,088 Closed

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.