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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
DPW
501
DiNuzzo Private Wealth
Pennsylvania
$604 -$918 -12 -67%
ACA
502
American Capital Advisory
Idaho
$504 +$382 +5 New
WCM
503
WealthTrak Capital Management
Virginia
$504 +$382 +5 New
HI
504
Harbour Investments
Wisconsin
$503 +$382 +5 New
RS
505
Rakuten Securities
Japan
$503 +$382 +5 New
TIM
506
Tortoise Investment Management
New York
$503 +$382 +5 New
MCM
507
MV Capital Management
Maryland
$403 +$306 +4 New
RCM
508
Raleigh Capital Management
North Carolina
$403 +$306 +4 New
SIC
509
SJS Investment Consulting
Ohio
$302 -$918 -12 -80%
PWA
510
Principia Wealth Advisory
Texas
$302 -$76 -1 -25%
NRG
511
Nemes Rush Group
Michigan
$302 +$229 +3 New
TWD
512
True Wealth Design
Ohio
$202 +$153 +2 New
HNW
513
High Note Wealth
Minnesota
$201
EP
514
Essential Partners
California
$201 +$153 +2 New
PWM
515
Parkworth Wealth Management
California
$101 -$153 -2 -67%
CWP
516
Concord Wealth Partners
Virginia
$101 +$76 +1 New
T. Rowe Price Investment Management
517
T. Rowe Price Investment Management
Maryland
-$113M -1,476,948 Closed
VPC
518
Vestal Point Capital
New York
-$82M -1,075,000 Closed
1832 Asset Management
519
1832 Asset Management
Ontario, Canada
-$37.2M -487,800 Closed
PBA
520
Paradigm Biocapital Advisors
New York
-$34.4M -451,359 Closed
SFM
521
Soros Fund Management
New York
-$23.4M -307,211 Closed
KCM
522
Kingdon Capital Management
New York
-$16.4M -215,000 Closed
RCM
523
RA Capital Management
Massachusetts
-$15.3M -200,000 Closed
CCM
524
Cutter Capital Management
New York
-$14.2M -186,384 Closed
SFI
525
Susquehanna Fundamental Investments
Pennsylvania
-$10.1M -132,925 Closed

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.