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669 hedge funds and large institutions have $35B invested in Insmed in 2026 Q1 according to their latest regulatory filings, with 98 funds opening new positions, 288 increasing their positions, 214 reducing their positions, and 93 closing their positions.

New
Increased
Maintained
Reduced
Closed

52% more call options, than puts

Call options by funds: $352M | Put options by funds: $232M

35% more repeat investments, than reductions

Existing positions increased: 288 | Existing positions reduced: 214

18% more funds holding in top 10

Funds holding in top 10: 2226 (+4)

5% more first-time investments, than exits

New positions opened: 98 | Existing positions closed: 93

0.72% more ownership

Funds ownership: 99.68%100.4% (+0.72%)

1% less funds holding

Funds holding: 676669 (-7)

6% less capital invested

Capital invested by funds: $37B → $35B (-$2.04B)

Holders
669
Holders Change
-7
Holders Change %
-1.04%
% of All Funds
8.24%
Holding in Top 10
26
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+18.18%
% of All Funds
0.32%
New
98
Increased
288
Reduced
214
Closed
93
Calls
$352M
Puts
$232M
Net Calls
+$120M
Net Calls Change
+$191M
Name Holding Trade Value Shares
Change
Change in
Stake
VFT
26
Vanguard Fiduciary Trust
Pennsylvania
$221M +$208M +1,354,516 New
Morgan Stanley
27
Morgan Stanley
New York
$218M -$46.2M -300,364 -18%
Northern Trust
28
Northern Trust
Illinois
$212M +$8.54M +55,562 +4%
CHP
29
Castle Hook Partners
New York
$208M +$2.49M +16,186 +1%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$206M -$19.6M -127,293 -9%
PBA
31
Paradigm Biocapital Advisors
New York
$205M +$193M +1,254,488 New
UBS AM
32
UBS AM
Illinois
$199M +$41.8M +271,719 +29%
Millennium Management
33
Millennium Management
New York
$189M -$23.7M -153,868 -12%
DFO
34
Duquesne Family Office
New York
$189M -$50.4M -327,662 -22%
NAMI
35
Nomura Asset Management International
Pennsylvania
$187M -$6.04M -39,290 -3%
Pictet Asset Management
36
Pictet Asset Management
Switzerland
$179M +$22M +143,285 +15%
Charles Schwab
37
Charles Schwab
California
$175M +$6.46M +42,035 +4%
Fiera Capital (Canada)
38
Fiera Capital (Canada)
Quebec, Canada
$167M +$4.47M +29,078 +3%
NM
39
NWI Management
New York
$166M +$3.93M +25,540 +3%
Goldman Sachs
40
Goldman Sachs
New York
$154M -$46.5M -302,267 -24%
American Century Companies
41
American Century Companies
Missouri
$151M +$114M +740,709 +400%
Principal Financial Group
42
Principal Financial Group
Iowa
$150M +$22.3M +145,106 +19%
William Blair Investment Management
43
William Blair Investment Management
Illinois
$148M -$49M -318,430 -26%
Adage Capital Partners
44
Adage Capital Partners
Massachusetts
$147M +$92.2M +600,000 +200%
Fidelity International
45
Fidelity International
Bermuda
$136M -$1.47M -9,562 -1%
Amundi
46
Amundi
France
$132M -$17.2M -112,021 -12%
Legal & General Group
47
Legal & General Group
United Kingdom
$129M +$37.9M +246,766 +46%
Raymond James Financial
48
Raymond James Financial
Florida
$121M -$631K -4,106 -0.5%
AllianceBernstein
49
AllianceBernstein
Tennessee
$120M +$7.07M +46,015 +7%
HRCM
50
Hood River Capital Management
Florida
$113M +$7.84M +50,977 +8%