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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
NS
426
NBC Securities
Alabama
$57K -$5.28K -69 -11%
BTI
427
Blue Trust Inc
Georgia
$56.8K -$26.1K -342 -38%
S
428
SignatureFD
Georgia
$53.8K -$25.4K -332 -38%
MA
429
Montag & Associates
Georgia
$52.1K +$76 +1 +0.2%
FDCDDQ
430
Federation des caisses Desjardins du Quebec
Quebec, Canada
$50.3K
BIG
431
Brooklyn Investment Group
New York
$50.1K +$34.9K +456 +1,086%
FFA
432
Farther Finance Advisors
California
$48.9K +$2.91K +38 +9%
CFB
433
Cullen/Frost Bankers
Texas
$41.9K +$4.66K +61 +17%
SAM
434
Smartleaf Asset Management
Massachusetts
$37.9K -$29.7K -388 -50%
Bessemer Group
435
Bessemer Group
New Jersey
$35K +$2.68K +35 +11%
PWAM
436
Private Wealth Asset Management
Iowa
$33.5K -$994 -13 -4%
FIA
437
FNY Investment Advisers
New York
$33K +$25.5K +334 New
Mitsubishi UFJ Asset Management
438
Mitsubishi UFJ Asset Management
Japan
$32.3K
RA
439
Rise Advisors
New York
$31.8K
AF
440
Allworth Financial
California
$31.2K +$2.45K +32 +12%
OP
441
ORG Partners
Indiana
$28.3K +$15K +196 +220%
HNB
442
Hilltop National Bank
Wyoming
$28.1K +$21.3K +279 New
IGAM
443
iA Global Asset Management
Quebec, Canada
$22K +$16.7K +218 New
VCM
444
Versant Capital Management
Arizona
$20.9K -$37.5K -490 -70%
UB
445
UMB Bank
Missouri
$18.9K +$1.07K +14 +8%
C
446
Covestor
United Kingdom
$17K
CIM
447
Contravisory Investment Management
Massachusetts
$16.7K +$12.7K +166 New
Jones Financial Companies
448
Jones Financial Companies
Missouri
$16.6K +$3.44K +45 +37%
A
449
AlphaQuest
New York
$13.8K +$3.67K +48 +54%
MPWT
450
MassMutual Private Wealth & Trust
Connecticut
$13.7K -$14.1K -185 -58%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.