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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
AB
401
ANB Bank
Colorado
$206K +$157K +2,051 New
LAM
402
Longboard Asset Management
Arizona
$205K +$156K +2,041 New
UCFA
403
United Capital Financial Advisors
Texas
$202K +$153K +2,006 New
YCM
404
Yousif Capital Management
Michigan
$201K +$153K +2,001 New
CWM
405
Cornerstone Wealth Management
Missouri
$201K +$153K +2,000 New
PA
406
Parallel Advisors
California
$198K +$2.06K +27 +1%
CC
407
Centiva Capital
New York
$188K +$143K +1,867 New
Carson Wealth (CWM LLC)
408
Carson Wealth (CWM LLC)
Nebraska
$174K -$24.5K -321 -16%
CWIG
409
Chung Wu Investment Group
Texas
$173K +$132K +1,720 New
MYIA
410
Mount Yale Investment Advisors
Colorado
$170K -$131K -1,712 -50%
Acadian Asset Management
411
Acadian Asset Management
Massachusetts
$116K -$43K -562 -33%
POIA
412
Pin Oak Investment Advisors
Texas
$110K
MCM
413
Manchester Capital Management
Vermont
$101K +$76.8K +1,004 New
SCM
414
Sterling Capital Management
North Carolina
$101K +$62.5K +818 +452%
FHA
415
First Horizon Advisors
Tennessee
$94.2K +$14.2K +186 +25%
GRP
416
Global Retirement Partners
California
$81.3K +$61.8K +808 New
GI
417
GAMMA Investing
California
$80.5K -$16K -209 -21%
TPW
418
Talon Private Wealth
Florida
$80.5K +$61.2K +800 New
SWM
419
Spire Wealth Management
Virginia
$70.1K +$918 +12 +2%
EWA
420
EverSource Wealth Advisors
Alabama
$66.8K +$20.1K +263 +66%
Daiwa Securities Group
421
Daiwa Securities Group
Japan
$64K +$2.29K +30 +5%
SPIA
422
Steward Partners Investment Advisory
New York
$61.8K -$10.6K -139 -18%
HNB
423
Huntington National Bank
Ohio
$61.2K -$4.59K -60 -9%
CA
424
Clearstead Advisors
Ohio
$61.1K +$14.5K +189 +45%
LI
425
LRI Investments
Florida
$58.6K +$44.5K +582 New

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.