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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
FT
326
Fiduciary Trust
Massachusetts
$533K -$79K -1,033 -16%
IB
327
Intrust Bank
Kansas
$524K -$51.8K -677 -12%
Envestnet Portfolio Solutions
328
Envestnet Portfolio Solutions
Illinois
$522K -$53.9K -705 -12%
P
329
Pitcairn
Pennsylvania
$513K -$63.8K -835 -14%
ECM
330
Everence Capital Management
Indiana
$513K
JFG
331
Jefferies Financial Group
New York
$501K +$190K +2,483 +99%
KBC Group
332
KBC Group
Belgium
$501K -$197K -2,575 -34%
CCM
333
Coldstream Capital Management
Washington
$501K +$18.7K +244 +5%
OIA
334
OneDigital Investment Advisors
Kansas
$496K -$22.6K -296 -6%
NEI
335
Northwest & Ethical Investments
Ontario, Canada
$488K +$260K +3,400 +227%
PAG
336
Private Advisor Group
New Jersey
$484K +$20.4K +267 +6%
CIBC Asset Management
337
CIBC Asset Management
Ontario, Canada
$481K
VCM
338
Voleon Capital Management
California
$480K +$364K +4,767 New
NIM
339
NEOS Investment Management
Connecticut
$480K -$338K -4,416 -48%
TE
340
Tema ETFs
New York
$480K -$338K -4,416 -48%
SLAM
341
Swiss Life Asset Management
$477K +$162K +2,119 +81%
Mirae Asset Global ETFs Holdings
342
Mirae Asset Global ETFs Holdings
Hong Kong
$477K -$8.01M -104,697 -96%
Commonwealth Equity Services
343
Commonwealth Equity Services
Massachusetts
$472K +$358K +4,688 New
AWS
344
Atria Wealth Solutions
New York
$469K -$67.4K -881 -16%
VIA
345
Virtus Investment Advisers
Connecticut
$462K -$30.5K -399 -8%
GFM
346
GF Fund Management
China
$461K
Focus Partners Wealth
347
Focus Partners Wealth
Massachusetts
$453K +$344K +4,503 New
OAM
348
Oxford Asset Management
United Kingdom
$453K +$344K +4,497 New
FDP
349
Financiere des Professionnels
Quebec, Canada
$452K +$343K +4,487 New
QCM
350
Quantinno Capital Management
New York
$450K +$67.1K +878 +24%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.