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669 hedge funds and large institutions have $35B invested in Insmed in 2026 Q1 according to their latest regulatory filings, with 98 funds opening new positions, 288 increasing their positions, 214 reducing their positions, and 93 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
669
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
26
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$352M
Puts
$232M
Net Calls
Net Calls Change

Top Buyers

1 +$497M
2 +$259M
3 +$248M
4
Capital World Investors
Capital World Investors
California
+$209M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$196M

Top Sellers

1 -$635M
2 -$355M
3 -$146M
4
JFG
Jefferies Financial Group
New York
-$142M
5
Holocene Advisors
Holocene Advisors
New York
-$139M
Name Holding Trade Value Shares
Change
Change in
Stake
EA
301
Emerald Advisers
Pennsylvania
$1.96M
PIMJS
302
PKO Investment Management Joint-Stock
Poland
$1.93M
A
303
AustralianSuper
Australia
$1.91M
FDCDDQ
304
Federation des caisses Desjardins du Quebec
Quebec, Canada
$1.88M
Jane Street
305
Jane Street
New York
$1.86M
DAM
306
Draper Asset Management
New York
$1.85M
ALMGDA
307
AG2R La Mondiale Gestion d'Actifs
France
$1.84M
VPIM
308
Vanguard Personalized Indexing Management
California
$1.83M
EFM
309
E Fund Management
China
$1.8M
CBU
310
CIBC Bancorp USA
Illinois
$1.8M
CF
311
Cantor Fitzgerald
New York
$1.8M
SAM
312
Simplify Asset Management
Nevada
$1.76M
Simplex Trading
313
Simplex Trading
Illinois
$1.75M
MSRPS
314
Maryland State Retirement & Pension System
Maryland
$1.71M
OIMU
315
Osmosis Investment Management UK
United Kingdom
$1.71M
PAS
316
Park Avenue Securities
New York
$1.69M
SCM
317
Soleus Capital Management
Connecticut
$1.68M
BG
318
Bellevue Group
Switzerland
$1.64M
GAM
319
Gotham Asset Management
New York
$1.64M
VAS
320
Vestmark Advisory Solutions
Massachusetts
$1.62M
VA
321
Vident Advisory
Georgia
$1.6M
TMAM
322
Tokio Marine Asset Management
Japan
$1.52M
M&T Bank
323
M&T Bank
New York
$1.5M
Group One Trading
324
Group One Trading
Illinois
$1.49M
Wealth Enhancement Advisory Services
325
Wealth Enhancement Advisory Services
Minnesota
$1.48M