559 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 127 funds opening new positions, 191 increasing their positions, 196 reducing their positions, and 72 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

7% less call options, than puts

Call options by funds: $610M | Put options by funds: $657M

15.75% less ownership

Funds ownership: 115.51%99.76% (-16%)

27% less funds holding in top 10

Funds holding in top 10: 3324 (-9)

Holders
559
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
24
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$610M
Puts
$657M
Net Calls
Net Calls Change

Top Buyers

1 +$1.07B
2 +$589M
3 +$330M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$322M
5
OAG
Orbis Allan Gray
Bermuda
+$249M
Name Holding Trade Value Shares
Change
Change in
Stake
OSAM
251
O'Shaughnessy Asset Management
Connecticut
$1.9M
FDCDDQ
252
Federation des caisses Desjardins du Quebec
Quebec, Canada
$1.9M
GAM
253
Groupama Asset Management
France
$1.9M
MMEA
254
Main Management ETF Advisors
California
$1.9M
BFM
255
Boothbay Fund Management
New York
$1.85M
QCM
256
Quantinno Capital Management
New York
$1.84M
EGM
257
Engineers Gate Manager
New York
$1.8M
EA
258
Emerald Advisers
Pennsylvania
$1.78M
EMFAT
259
Emerald Mutual Fund Advisers Trust
Pennsylvania
$1.77M
MA
260
MYDA Advisors
New York
$1.73M
APM
261
Avidity Partners Management
Texas
$1.67M
PA
262
Profund Advisors
Maryland
$1.64M
MIM
263
MetLife Investment Management
New Jersey
$1.64M
Parallax Volatility Advisers
264
Parallax Volatility Advisers
California
$1.6M
FMI
265
F/M Investments
District of Columbia
$1.59M
Prudential Financial
266
Prudential Financial
New Jersey
$1.58M
TI
267
Tidal Investments
Wisconsin
$1.56M
QCM
268
Qsemble Capital Management
New York
$1.54M
PAS
269
Park Avenue Securities
New York
$1.54M
Nisa Investment Advisors
270
Nisa Investment Advisors
Missouri
$1.51M
DAM
271
Draper Asset Management
New York
$1.49M
NICM
272
Neo Ivy Capital Management
New York
$1.4M
YMRC
273
Yorktown Management & Research Company
Virginia
$1.38M
VPIM
274
Vanguard Personalized Indexing Management
California
$1.38M
MSRPS
275
Maryland State Retirement & Pension System
Maryland
$1.34M