Insmed
INSM
566 hedge funds and large institutions have $30.3B invested in Insmed in 2025 Q3 according to their latest regulatory filings, with 130 funds opening new positions, 194 increasing their positions, 197 reducing their positions, and 72 closing their positions.
81% more first-time investments, than exits
New positions opened: 130 | Existing positions closed: 72
43% more capital invested
Capital invested by funds: $21.2B → $30.3B (+$9.17B)
10% more funds holding
Funds holding: 516 → 566 (+50)
2% less repeat investments, than reductions
Existing positions increased: 194 | Existing positions reduced: 197
7% less call options, than puts
Call options by funds: $610M | Put options by funds: $657M
15.75% less ownership
Funds ownership: 115.51% → 99.76% (-16%)
27% less funds holding in top 10
Funds holding in top 10: 33 → 24 (-9)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JP Morgan Chase
New York
|
+$908M |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
+$501M |
| 3 |
Vanguard Group
Malvern,
Pennsylvania
|
+$281M |
| 4 |
D.E. Shaw & Co
New York
|
+$274M |
| 5 |
OAG
Orbis Allan Gray
Hamilton,
Bermuda
|
+$212M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$527M |
| 2 |
Adage Capital Partners
Boston,
Massachusetts
|
-$197M |
| 3 |
DTC
Deep Track Capital
Greenwich,
Connecticut
|
-$176M |
| 4 |
Janus Henderson Group
London,
United Kingdom
|
-$134M |
| 5 |
BBA
Baker Bros. Advisors
New York
|
-$124M |
INSM Hedge Fund Activity: Q3 2025 in Review
566 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q3 2025, worth a combined $30.3B — up 43% from $21.2B a quarter earlier.
Buyers outnumbered sellers: 130 funds opened new INSM positions and 72 closed out — a net gain of 58 holders — while 194 added to existing stakes and 197 trimmed.
The largest buyer was JP Morgan Chase, adding an estimated $908M. The largest seller was T. Rowe Price Associates, cutting an estimated $527M.
- 566 institutional investors held Insmed (INSM) as of Q3 2025, up from 516 in Q2 2025.
- Funds reported $30.3B of Insmed stock for Q3 2025, up 43% quarter-over-quarter.
- 130 funds opened new Insmed positions in Q3 2025 and 72 closed out, a net change of +58 holders.
- The largest Insmed buyer in Q3 2025 was JP Morgan Chase, an estimated $908M added.
- The largest Insmed seller in Q3 2025 was T. Rowe Price Associates, an estimated $527M sold.
Based on aggregated 13F filings for Q3 2025.