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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Cetera Investment Advisers
226
Cetera Investment Advisers
Illinois
$3.17M +$824K +10,783 +52%
ACH
227
ArrowMark Colorado Holdings
Colorado
$3.02M
Bank of Montreal
228
Bank of Montreal
Ontario, Canada
$2.99M -$55.1K -721 -2%
Mariner
229
Mariner
Kansas
$2.96M -$189K -2,473 -8%
Cerity Partners
230
Cerity Partners
New York
$2.83M -$252K -3,297 -10%
Skandinaviska Enskilda Banken (SEB)
231
Skandinaviska Enskilda Banken (SEB)
Sweden
$2.8M
SRL
232
Scientech Research LLC
New Jersey
$2.78M +$2.11M +27,642 New
CL
233
CSS LLC
Illinois
$2.76M +$2.09M +27,375 New
RCAP
234
Resolute Capital Asset Partners
Colorado
$2.75M +$2.09M +27,301 New
UOC
235
UBS O'Connor
Illinois
$2.65M +$66.8K +874 +3%
Baird Financial Group
236
Baird Financial Group
Wisconsin
$2.59M +$1.97M +25,721 New
EMFAT
237
Emerald Mutual Fund Advisers Trust
Pennsylvania
$2.56M -$25.1M -328,407 -93%
X
238
Xponance
Pennsylvania
$2.5M +$878K +11,482 +86%
FMI
239
F/M Investments
District of Columbia
$2.37M -$198K -2,592 -10%
AFG
240
Atomi Financial Group
New York
$2.32M -$178K -2,331 -9%
Calamos Advisors
241
Calamos Advisors
Illinois
$2.31M -$1.25M -16,349 -42%
WG
242
Winton Group
United Kingdom
$2.24M +$1.7M +22,268 New
QT
243
Quantbot Technologies
New York
$2.22M +$1.69M +22,067 New
KCM
244
Kennedy Capital Management
Missouri
$2.2M -$956K -12,500 -36%
OAM
245
Oppenheimer Asset Management
New York
$2.15M +$110K +1,439 +7%
PD
246
Point72 (DIFC)
United Arab Emirates
$1.97M +$1.5M +19,580 New
PA
247
Profund Advisors
Maryland
$1.97M -$959K -12,539 -39%
Public Employees Retirement Association of Colorado
248
Public Employees Retirement Association of Colorado
Colorado
$1.94M -$24.2K -316 -2%
SC
249
SummitTX Capital
Texas
$1.92M +$88.2K +1,153 +6%
Parallax Volatility Advisers
250
Parallax Volatility Advisers
California
$1.91M -$1.6M -20,897 -52%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.