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Structure Therapeutics

196 hedge funds and large institutions have $4.64B invested in Structure Therapeutics in 2025 Q4 according to their latest regulatory filings, with 70 funds opening new positions, 52 increasing their positions, 62 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

26% more funds holding

Funds holding: 156196 (+40)

11.44% more ownership

Funds ownership: 98.33%109.77% (+11%)

16% less repeat investments, than reductions

Existing positions increased: 52 | Existing positions reduced: 62

Holders
196
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
16
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$62.6M
Puts
$18.2M
Net Calls
Net Calls Change

Top Sellers

1 -$45.8M
2 -$42.5M
3 -$38.3M
4
Invesco
Invesco
Georgia
-$18M
5
CCM
Catalio Capital Management
New York
-$16.3M
Name Holding Trade Value Shares
Change
Change in
Stake
BG
51
Bellevue Group
Switzerland
$10.1M
EP
52
Eversept Partners
New York
$8.87M
WP
53
Woodline Partners
California
$8.62M
Renaissance Technologies
54
Renaissance Technologies
New York
$8.01M
Alyeska Investment Group
55
Alyeska Investment Group
Illinois
$8M
JFG
56
Jefferies Financial Group
New York
$7.16M
RI
57
RTW Investments
New York
$6.96M
JG
58
Jain Global
New York
$6.95M
SFI
59
Susquehanna Fundamental Investments
Pennsylvania
$6.93M
Two Sigma Investments
60
Two Sigma Investments
New York
$6.65M
SC
61
SummitTX Capital
Texas
$6.58M
NCM
62
NEXTBio Capital Management
California
$6.57M
Manulife (Manufacturers Life Insurance)
63
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$6.53M
Simplex Trading
64
Simplex Trading
Illinois
$6.45M
BC
65
Birchview Capital
Vermont
$6.26M
BGI
66
B Group Inc
Texas
$6.26M
SCM
67
Soleus Capital Management
Connecticut
$6.26M
TI
68
Trexquant Investment
Connecticut
$6.26M
PIM
69
Platinum Investment Management
Australia
$6.11M
BHCM
70
Brevan Howard Capital Management
Jersey
$5.96M
PCM
71
Peregrine Capital Management
Minnesota
$5.86M
Universal-Beteiligungs- und Servicegesellschaft
72
Universal-Beteiligungs- und Servicegesellschaft
Germany
$5.78M
NAMI
73
Nomura Asset Management International
Pennsylvania
$5.75M
Verition Fund Management
74
Verition Fund Management
Connecticut
$5.44M
BCM
75
Boxer Capital Management
California
$5.22M