Guardant Health
601 hedge funds and large institutions have $20B invested in Guardant Health in 2026 Q2 according to their latest regulatory filings, with 161 funds opening new positions, 199 increasing their positions, 181 reducing their positions, and 41 closing their positions.
293% more first-time investments, than exits
New positions opened: 161 | Existing positions closed: 41
64% more funds holding in top 10
Funds holding in top 10: 11 → 18 (+7)
60% more capital invested
Capital invested by funds: $12.5B → $20B (+$7.53B)
24% more funds holding
Funds holding: 486 → 601 (+115)
10% more repeat investments, than reductions
Existing positions increased: 199 | Existing positions reduced: 181
4% more call options, than puts
Call options by funds: $154M | Put options by funds: $148M
2.11% less ownership
Funds ownership: 103.11% → 101% (-2.1%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Jane Street
New York
|
+$193M |
| 2 |
Ameriprise
Minneapolis,
Minnesota
|
+$189M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$149M |
| 4 |
D.E. Shaw & Co
New York
|
+$90.1M |
| 5 |
HF
HRT Financial
New York
|
+$76.6M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
-$428M |
| 2 |
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
-$171M |
| 3 |
Geode Capital Management
Boston,
Massachusetts
|
-$107M |
| 4 |
Alyeska Investment Group
Chicago,
Illinois
|
-$91.5M |
| 5 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
-$80.2M |
GH Hedge Fund Activity: Q2 2026 in Review
601 of the 8,349 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q2 2026, worth a combined $20B — up 60% from $12.5B a quarter earlier.
Buyers outnumbered sellers: 161 funds opened new GH positions and 41 closed out — a net gain of 120 holders — while 199 added to existing stakes and 181 trimmed.
The largest buyer was Jane Street, adding an estimated $193M. The largest seller was BlackRock, cutting an estimated $428M.
- 601 institutional investors held Guardant Health (GH) as of Q2 2026, up from 486 in Q1 2026.
- Funds reported $20B of Guardant Health stock for Q2 2026, up 60% quarter-over-quarter.
- 161 funds opened new Guardant Health positions in Q2 2026 and 41 closed out, a net change of +120 holders.
- The largest Guardant Health buyer in Q2 2026 was Jane Street, an estimated $193M added.
- The largest Guardant Health seller in Q2 2026 was BlackRock, an estimated $428M sold.
Based on aggregated 13F filings for Q2 2026.