Guardant Health
485 hedge funds and large institutions have $12.5B invested in Guardant Health in 2026 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 193 increasing their positions, 158 reducing their positions, and 78 closing their positions.
22% more repeat investments, than reductions
Existing positions increased: 193 | Existing positions reduced: 158
0.89% less ownership
Funds ownership: 103.99% → 103.11% (-0.89%)
6% less first-time investments, than exits
New positions opened: 73 | Existing positions closed: 78
2% less funds holding
Funds holding: 497 → 485 (-12)
7% less capital invested
Capital invested by funds: $13.4B → $12.5B (-$883M)
15% less funds holding in top 10
Funds holding in top 10: 13 → 11 (-2)
29% less call options, than puts
Call options by funds: $78.8M | Put options by funds: $112M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Two Sigma Investments
New York
|
+$207M |
| 2 |
Goldman Sachs
New York
|
+$182M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$173M |
| 4 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$139M |
| 5 |
William Blair Investment Management
Chicago,
Illinois
|
+$95.5M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
-$104M |
| 2 |
Jennison Associates
New York
|
-$97M |
| 3 |
Point72 Asset Management
Stamford,
Connecticut
|
-$80.6M |
| 4 |
DCM
Driehaus Capital Management
Chicago,
Illinois
|
-$62.1M |
| 5 |
Balyasny Asset Management
Chicago,
Illinois
|
-$51.6M |
GH Hedge Fund Activity: Q1 2026 in Review
485 of the 8,182 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q1 2026, worth a combined $12.5B — down 6.6% from $13.4B a quarter earlier.
Sellers outnumbered buyers: 78 funds closed out of GH and 73 opened new positions — a net loss of 5 holders — while 158 trimmed existing stakes and 193 added.
The largest buyer was Two Sigma Investments, adding an estimated $207M. The largest seller was Baillie Gifford & Co, cutting an estimated $104M.
- 485 institutional investors held Guardant Health (GH) as of Q1 2026, down from 497 in Q4 2025.
- Funds reported $12.5B of Guardant Health stock for Q1 2026, down 6.6% quarter-over-quarter.
- 73 funds opened new Guardant Health positions in Q1 2026 and 78 closed out, a net change of -5 holders.
- The largest Guardant Health buyer in Q1 2026 was Two Sigma Investments, an estimated $207M added.
- The largest Guardant Health seller in Q1 2026 was Baillie Gifford & Co, an estimated $104M sold.
Based on aggregated 13F filings for Q1 2026.