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Guardant Health

364 hedge funds and large institutions have $6.47B invested in Guardant Health in 2025 Q2 according to their latest regulatory filings, with 69 funds opening new positions, 128 increasing their positions, 115 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

57% more first-time investments, than exits

New positions opened: 69 | Existing positions closed: 44

27% more capital invested

Capital invested by funds: $5.1B → $6.47B (+$1.37B)

11% more repeat investments, than reductions

Existing positions increased: 128 | Existing positions reduced: 115

7% more funds holding

Funds holding: 341364 (+23)

3.34% more ownership

Funds ownership: 97%100.34% (+3.3%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

30% less call options, than puts

Call options by funds: $89.1M | Put options by funds: $126M

Holders
364
Holders Change
+23
Holders Change %
+6.74%
% of All Funds
4.79%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
69
Increased
128
Reduced
115
Closed
44
Calls
$89.1M
Puts
$126M
Net Calls
-$37.3M
Net Calls Change
-$4.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$633M +$3.87M +86,643 +0.7%
BlackRock
2
BlackRock
New York
$571M -$8.68M -194,410 -2%
Capital International Investors
3
Capital International Investors
California
$259M -$7.65M -171,266 -3%
Baillie Gifford & Co
4
Baillie Gifford & Co
United Kingdom
$250M -$11.2M -251,225 -5%
DTC
5
Deep Track Capital
Connecticut
$221M -$53.3M -1,193,721 -22%
Invesco
6
Invesco
Georgia
$185M +$34.1M +763,834 +27%
EAM
7
Eventide Asset Management
Massachusetts
$180M -$4.81M -107,775 -3%
CCM
8
Cadian Capital Management
New York
$165M -$63.2M -1,415,870 -31%
Citadel Advisors
9
Citadel Advisors
Florida
$153M -$29.4M -658,360 -18%
UBS AM
10
UBS AM
Illinois
$153M +$7.01M +156,948 +6%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$152M +$585K +13,088 +0.5%
State Street
12
State Street
Massachusetts
$148M +$1.77M +39,626 +1%
AIM
13
ARK Investment Management
Florida
$147M +$63.2M +1,414,381 +100%
Millennium Management
14
Millennium Management
New York
$142M +$72.6M +1,625,148 +148%
DCM
15
Driehaus Capital Management
Illinois
$129M +$24.2M +542,527 +28%
Two Sigma Advisers
16
Two Sigma Advisers
New York
$124M +$625K +14,000 +0.6%
Franklin Resources
17
Franklin Resources
California
$121M +$45.5M +1,018,144 +78%
Fuller & Thaler Asset Management
18
Fuller & Thaler Asset Management
California
$114M +$10.4M +232,108 +12%
Sumitomo Mitsui Trust Group
19
Sumitomo Mitsui Trust Group
Japan
$106M +$30.1M +673,411 +50%
NAMA
20
Nikko Asset Management Americas
New York
$106M +$30.1M +673,438 +50%
Wellington Management Group
21
Wellington Management Group
Massachusetts
$100M -$3.21M -71,820 -4%
Two Sigma Investments
22
Two Sigma Investments
New York
$96.5M +$1.28M +28,748 +2%
T. Rowe Price Associates
23
T. Rowe Price Associates
Maryland
$91.9M +$50.7M +1,136,068 +180%
Federated Hermes
24
Federated Hermes
Pennsylvania
$76.3M +$27.5M +615,429 +72%
Norges Bank
25
Norges Bank
Norway
$64.1M +$878K +19,662 +2%

GH Hedge Fund Activity: Q2 2025 in Review

364 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q2 2025, worth a combined $6.47B — up 27% from $5.1B a quarter earlier.

Buyers outnumbered sellers: 69 funds opened new GH positions and 44 closed out — a net gain of 25 holders — while 128 added to existing stakes and 115 trimmed.

The largest buyer was Millennium Management, adding an estimated $72.6M. The largest seller was Cadian Capital Management, cutting an estimated $63.2M.

  • 364 institutional investors held Guardant Health (GH) as of Q2 2025, up from 341 in Q1 2025.
  • Funds reported $6.47B of Guardant Health stock for Q2 2025, up 27% quarter-over-quarter.
  • 69 funds opened new Guardant Health positions in Q2 2025 and 44 closed out, a net change of +25 holders.
  • The largest Guardant Health buyer in Q2 2025 was Millennium Management, an estimated $72.6M added.
  • The largest Guardant Health seller in Q2 2025 was Cadian Capital Management, an estimated $63.2M sold.

Based on aggregated 13F filings for Q2 2025.