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Guardant Health

394 hedge funds and large institutions have $7.65B invested in Guardant Health in 2025 Q3 according to their latest regulatory filings, with 71 funds opening new positions, 134 increasing their positions, 132 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more first-time investments, than exits

New positions opened: 71 | Existing positions closed: 39

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

18% more capital invested

Capital invested by funds: $6.47B → $7.65B (+$1.19B)

8% more funds holding

Funds holding: 364394 (+30)

2% more repeat investments, than reductions

Existing positions increased: 134 | Existing positions reduced: 132

10% less call options, than puts

Call options by funds: $156M | Put options by funds: $173M

2.09% less ownership

Funds ownership: 100.34%98.24% (-2.1%)

Holders
394
Holders Change
+30
Holders Change %
+8.24%
% of All Funds
5.17%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.12%
New
71
Increased
134
Reduced
132
Closed
39
Calls
$156M
Puts
$173M
Net Calls
-$16.8M
Net Calls Change
+$20.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$744M -$14.1M -259,191 -2%
BlackRock
2
BlackRock
New York
$714M +$24.5M +449,845 +4%
Baillie Gifford & Co
3
Baillie Gifford & Co
United Kingdom
$320M +$17.3M +317,906 +7%
Invesco
4
Invesco
Georgia
$308M +$74.6M +1,371,042 +39%
Capital International Investors
5
Capital International Investors
California
$293M -$15.6M -287,217 -6%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$264M +$134M +2,456,061 +139%
DTC
7
Deep Track Capital
Connecticut
$260M -$5.22M -95,914 -2%
EAM
8
Eventide Asset Management
Massachusetts
$208M -$7.49M -137,625 -4%
Wellington Management Group
9
Wellington Management Group
Massachusetts
$203M +$72.1M +1,326,116 +69%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$184M +$867K +15,942 +0.5%
Franklin Resources
11
Franklin Resources
California
$183M +$33M +606,368 +26%
State Street
12
State Street
Massachusetts
$174M -$2.82M -51,888 -2%
Fuller & Thaler Asset Management
13
Fuller & Thaler Asset Management
California
$148M +$9.34M +171,739 +8%
UBS AM
14
UBS AM
Illinois
$141M -$36.6M -672,119 -23%
DCM
15
Driehaus Capital Management
Illinois
$134M -$17.6M -323,298 -13%
CCM
16
Cadian Capital Management
New York
$134M -$56.5M -1,038,026 -33%
Two Sigma Advisers
17
Two Sigma Advisers
New York
$132M -$14.6M -269,000 -11%
Alyeska Investment Group
18
Alyeska Investment Group
Illinois
$114M +$99.6M +1,831,318 New
Two Sigma Investments
19
Two Sigma Investments
New York
$113M -$2.79M -51,280 -3%
Federated Hermes
20
Federated Hermes
Pennsylvania
$111M +$16.9M +310,931 +21%
Lord, Abbett & Co
21
Lord, Abbett & Co
New Jersey
$95.2M +$34.6M +635,919 +72%
Goldman Sachs
22
Goldman Sachs
New York
$94.1M +$19.6M +359,505 +31%
RI
23
RTW Investments
New York
$92.5M +$34M +624,532 +73%
Jennison Associates
24
Jennison Associates
New York
$91.9M +$41.1M +755,827 +106%
UBS Group
25
UBS Group
Switzerland
$91M +$14.9M +273,232 +23%

GH Hedge Fund Activity: Q3 2025 in Review

394 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q3 2025, worth a combined $7.65B — up 18% from $6.47B a quarter earlier.

Buyers outnumbered sellers: 71 funds opened new GH positions and 39 closed out — a net gain of 32 holders — while 134 added to existing stakes and 132 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $134M. The largest seller was Citadel Advisors, cutting an estimated $143M.

  • 394 institutional investors held Guardant Health (GH) as of Q3 2025, up from 364 in Q2 2025.
  • Funds reported $7.65B of Guardant Health stock for Q3 2025, up 18% quarter-over-quarter.
  • 71 funds opened new Guardant Health positions in Q3 2025 and 39 closed out, a net change of +32 holders.
  • The largest Guardant Health buyer in Q3 2025 was T. Rowe Price Associates, an estimated $134M added.
  • The largest Guardant Health seller in Q3 2025 was Citadel Advisors, an estimated $143M sold.

Based on aggregated 13F filings for Q3 2025.