|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$332M
|
-$3.69M
|
-288,177
|
-1%
|
|
|
2
|
Perceptive Advisors
New York
|
$331M
|
–
|
–
|
–
|
|
|
3
|
Avoro Capital Advisors
New York
|
$323M
|
–
|
–
|
–
|
|
|
4
|
|
$269M
|
-$1.77M
|
-138,690
|
-0.6%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$222M
|
+$46.2M
|
+3,613,621
|
+24%
|
|
|
6
|
|
$185M
|
-$27.6M
|
-2,157,374
|
-12%
|
|
|
7
|
Janus Henderson Group
London,
|
$163M
|
+$29.5M
|
+2,307,385
|
+20%
|
|
|
8
|
Redmile Group
San Francisco,
California
|
$156M
|
-$20.1M
|
-1,571,035
|
-11%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$147M
|
-$9.22M
|
-720,584
|
-5%
|
|
|
10
|
William Blair Investment Management
Chicago,
Illinois
|
$136M
|
-$1.54M
|
-120,747
|
-1%
|
|
|
11
|
|
$114M
|
-$46.3M
|
-3,623,049
|
-27%
|
|
|
12
|
Palo Alto Investors
Palo Alto,
California
|
$110M
|
-$13.2M
|
-1,029,613
|
-10%
|
|
|
13
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$83.3M
|
-$1.85M
|
-144,277
|
-2%
|
|
|
14
|
Pictet Asset Management
Carouge,
Switzerland
|
$79.9M
|
-$2.91M
|
-227,224
|
-3%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$73.2M
|
+$3.32M
|
+259,441
|
+4%
|
|
|
16
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$61.5M
|
+$2.05M
|
+160,685
|
+3%
|
|
|
17
|
American Century Companies
Kansas City,
Missouri
|
$56.6M
|
+$2.8M
|
+218,832
|
+5%
|
|
|
18
|
|
$51.4M
|
+$23.4M
|
+1,828,326
|
+72%
|
|
|
19
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$51.3M
|
-$18.3M
|
-1,427,663
|
-25%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$37.2M
|
+$3.98M
|
+311,331
|
+11%
|
|
|
21
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$31.1M
|
+$2.9M
|
+226,447
|
+9%
|
|
|
22
|
Novo Holdings A/S
Hellerup,
Denmark
|
$29.4M
|
–
|
–
|
–
|
|
|
23
|
Bank of America
Charlotte,
North Carolina
|
$29.2M
|
-$2.89M
|
-226,132
|
-8%
|
|
|
24
|
|
$29.1M
|
–
|
–
|
–
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$27.4M
|
+$742K
|
+58,041
|
+3%
|
|
