|
1
|
Perceptive Advisors
New York
|
$338M
|
+$3.04M
|
+270,000
|
+1%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$327M
|
–
|
–
|
–
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$324M
|
+$7.51M
|
+667,309
|
+3%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$247M
|
-$16.5M
|
-1,469,402
|
-7%
|
|
|
5
|
|
$246M
|
+$2.7M
|
+239,526
|
+1%
|
|
|
6
|
|
$218M
|
+$7.38M
|
+655,841
|
+4%
|
|
|
7
|
Janus Henderson Group
London,
|
$167M
|
-$12.2M
|
-1,081,566
|
-7%
|
|
|
8
|
|
$165M
|
-$8.9M
|
-790,337
|
-6%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$148M
|
+$716K
|
+63,627
|
+0.5%
|
|
|
10
|
Palo Alto Investors
Palo Alto,
California
|
$128M
|
+$7.27M
|
+645,948
|
+7%
|
|
|
11
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$103M
|
+$55.7M
|
+4,945,650
|
+142%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$99M
|
+$574K
|
+50,972
|
+0.6%
|
|
|
13
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$85M
|
+$904K
|
+80,286
|
+1%
|
|
|
14
|
|
$65.9M
|
+$11.7M
|
+1,043,346
|
+24%
|
|
|
15
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$63.4M
|
+$13.2M
|
+1,172,602
|
+29%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$59.7M
|
+$1.89M
|
+167,542
|
+4%
|
|
|
17
|
|
$48.8M
|
–
|
–
|
–
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$32.9M
|
+$381K
|
+33,885
|
+1%
|
|
|
19
|
Fidelity Investments
Boston,
Massachusetts
|
$30.4M
|
-$3.4M
|
-302,420
|
-11%
|
|
|
20
|
Bank of America
Charlotte,
North Carolina
|
$28.7M
|
+$3.24M
|
+287,852
|
+14%
|
|
|
21
|
Boxer Capital
San Diego,
California
|
$28.4M
|
–
|
–
|
–
|
|
|
22
|
|
$27.3M
|
-$7.54M
|
-670,171
|
-23%
|
|
|
23
|
William Blair Investment Management
Chicago,
Illinois
|
$25.7M
|
+$178K
|
+15,822
|
+0.8%
|
|
|
24
|
Novo Holdings A/S
Hellerup,
Denmark
|
$25.6M
|
-$46.2K
|
-4,100
|
-0.2%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$25.2M
|
+$501K
|
+44,518
|
+2%
|
|
