|
1
|
Perceptive Advisors
New York
|
$289M
|
-$5.44M
|
-660,313
|
-2%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$288M
|
+$51.9M
|
+6,300,000
|
+31%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$276M
|
+$617K
|
+74,919
|
+0.3%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$238M
|
-$1.4M
|
-170,495
|
-0.8%
|
|
|
5
|
|
$217M
|
+$5.41M
|
+656,857
|
+3%
|
|
|
6
|
|
$197M
|
+$8.99M
|
+1,092,228
|
+6%
|
|
|
7
|
Janus Henderson Group
London,
|
$180M
|
+$9.53M
|
+1,157,528
|
+7%
|
|
|
8
|
|
$170M
|
+$2.57M
|
+312,291
|
+2%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$149M
|
+$16.3M
|
+1,983,752
|
+17%
|
|
|
10
|
Wellington Management Group
Boston,
Massachusetts
|
$118M
|
-$128M
|
-15,594,363
|
-59%
|
|
|
11
|
Palo Alto Investors
Palo Alto,
California
|
$106M
|
-$461K
|
-55,987
|
-0.6%
|
|
|
12
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$72.7M
|
+$1.85M
|
+224,367
|
+3%
|
|
|
13
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$67.6M
|
+$5.28M
|
+641,299
|
+11%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$50M
|
+$1.18M
|
+143,003
|
+3%
|
|
|
15
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$43.9M
|
-$608K
|
-73,876
|
-2%
|
|
|
16
|
|
$43M
|
–
|
–
|
–
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$40M
|
+$18M
|
+2,185,467
|
+142%
|
|
|
18
|
|
$31.9M
|
-$623K
|
-75,702
|
-2%
|
|
|
19
|
|
$30.6M
|
+$3.13M
|
+379,744
|
+15%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$28.9M
|
+$45K
|
+5,461
|
+0.2%
|
|
|
21
|
Novo Holdings A/S
Hellerup,
Denmark
|
$28.3M
|
+$616K
|
+74,789
|
+3%
|
|
|
22
|
William Blair Investment Management
Chicago,
Illinois
|
$27.4M
|
+$133K
|
+16,194
|
+0.6%
|
|
|
23
|
Boxer Capital
San Diego,
California
|
$25M
|
–
|
–
|
–
|
|
|
24
|
Balyasny Asset Management
Chicago,
Illinois
|
$23.1M
|
+$17.7M
|
+2,153,084
|
New
|
|
|
25
|
Fidelity Investments
Boston,
Massachusetts
|
$22M
|
+$2.79M
|
+338,528
|
+20%
|
|
