|
1
|
Perceptive Advisors
New York
|
$286M
|
+$5.32M
|
+477,385
|
+2%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$280M
|
–
|
–
|
–
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$270M
|
+$1.55M
|
+138,973
|
+0.5%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$227M
|
-$4.9M
|
-439,700
|
-2%
|
|
|
5
|
|
$208M
|
-$3.91M
|
-351,306
|
-2%
|
|
|
6
|
|
$179M
|
-$12.6M
|
-1,130,067
|
-6%
|
|
|
7
|
Janus Henderson Group
London,
|
$154M
|
-$22.3M
|
-2,004,026
|
-12%
|
|
|
8
|
|
$150M
|
-$17M
|
-1,526,402
|
-10%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$126M
|
-$21.1M
|
-1,896,103
|
-14%
|
|
|
10
|
Palo Alto Investors
Palo Alto,
California
|
$103M
|
–
|
–
|
–
|
|
|
11
|
Wellington Management Group
Boston,
Massachusetts
|
$84.1M
|
-$33.1M
|
-2,968,369
|
-27%
|
|
|
12
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$71.8M
|
+$1.23M
|
+110,515
|
+2%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$49.3M
|
+$709K
|
+63,632
|
+1%
|
|
|
14
|
|
$45.5M
|
+$16.8M
|
+1,511,838
|
+53%
|
|
|
15
|
|
$41.8M
|
–
|
–
|
–
|
|
|
16
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$38.1M
|
-$739K
|
-66,317
|
-2%
|
|
|
17
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$36.4M
|
+$31.7M
|
+2,842,220
|
+442%
|
|
|
18
|
|
$30.3M
|
-$727K
|
-65,240
|
-2%
|
|
|
19
|
Fidelity Investments
Boston,
Massachusetts
|
$29.2M
|
+$8.29M
|
+744,451
|
+36%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$27.8M
|
-$339K
|
-30,413
|
-1%
|
|
|
21
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$27.4M
|
+$9.85M
|
+884,400
|
+51%
|
|
|
22
|
Boxer Capital
San Diego,
California
|
$24.3M
|
–
|
–
|
–
|
|
|
23
|
Novo Holdings A/S
Hellerup,
Denmark
|
$21.9M
|
-$5.96M
|
-535,000
|
-20%
|
|
|
24
|
William Blair Investment Management
Chicago,
Illinois
|
$21.8M
|
-$5.15M
|
-462,242
|
-18%
|
|
|
25
|
Bank of America
Charlotte,
North Carolina
|
$21.6M
|
+$1.2M
|
+107,592
|
+5%
|
|
