|
1
|
Perceptive Advisors
New York
|
$355M
|
-$879K
|
-60,316
|
-0.2%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$327M
|
-$13.5M
|
-925,169
|
-4%
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$326M
|
-$27.2M
|
-1,868,888
|
-7%
|
|
|
4
|
|
$296M
|
-$18.8M
|
-1,287,010
|
-6%
|
|
|
5
|
Janus Henderson Group
London,
|
$199M
|
+$33.7M
|
+2,312,500
|
+20%
|
|
|
6
|
|
$157M
|
+$40.3M
|
+2,768,405
|
+33%
|
|
|
7
|
Avoro Capital Advisors
New York
|
$153M
|
-$2.19M
|
-150,000
|
-1%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$126M
|
-$19.7M
|
-1,354,448
|
-13%
|
|
|
9
|
|
$117M
|
+$3.75M
|
+257,075
|
+3%
|
|
|
10
|
Palo Alto Investors
Palo Alto,
California
|
$111M
|
+$7.76M
|
+532,400
|
+7%
|
|
|
11
|
|
$104M
|
+$4.32M
|
+296,215
|
+4%
|
|
|
12
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$84.8M
|
-$3.72M
|
-255,357
|
-4%
|
|
|
13
|
Wellington Management Group
Boston,
Massachusetts
|
$84.8M
|
-$10.5M
|
-720,136
|
-11%
|
|
|
14
|
Jennison Associates
New York
|
$75.7M
|
+$4.01M
|
+274,966
|
+5%
|
|
|
15
|
Fidelity Investments
Boston,
Massachusetts
|
$62M
|
-$51.8M
|
-3,555,083
|
-45%
|
|
|
16
|
ClearBridge Investments
New York
|
$59.8M
|
+$3.6M
|
+247,103
|
+6%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$54.2M
|
-$485K
|
-33,299
|
-0.9%
|
|
|
18
|
Victory Capital Management
San Antonio,
Texas
|
$54M
|
+$4.63M
|
+317,779
|
+9%
|
|
|
19
|
|
$52.4M
|
-$6.37M
|
-437,019
|
-11%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$46.7M
|
-$2.99M
|
-205,250
|
-6%
|
|
|
21
|
|
$42.4M
|
-$7.29M
|
-500,000
|
-14%
|
|
|
22
|
Eagle Asset Management
St Petersburg,
Florida
|
$39M
|
-$173K
|
-11,855
|
-0.4%
|
|
|
23
|
Nuveen
Charlotte,
North Carolina
|
$38.1M
|
-$3M
|
-205,939
|
-7%
|
|
|
24
|
|
$35.8M
|
-$2.12M
|
-145,551
|
-5%
|
|
|
25
|
Boxer Capital
San Diego,
California
|
$32.8M
|
–
|
–
|
–
|
|
