|
1
|
Perceptive Advisors
New York
|
$254M
|
+$35.2M
|
+3,438,114
|
+15%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$234M
|
-$2.46M
|
-240,799
|
-1%
|
|
|
3
|
Wellington Management Group
Boston,
Massachusetts
|
$232M
|
+$88.2M
|
+8,624,249
|
+55%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$199M
|
–
|
–
|
–
|
|
|
5
|
|
$187M
|
-$7.32M
|
-716,072
|
-4%
|
|
|
6
|
Avoro Capital Advisors
New York
|
$169M
|
+$53.5M
|
+5,229,273
|
+42%
|
|
|
7
|
|
$146M
|
+$20.4M
|
+1,996,622
|
+15%
|
|
|
8
|
|
$112M
|
+$293K
|
+28,607
|
+0.2%
|
|
|
9
|
Palo Alto Investors
Palo Alto,
California
|
$96.6M
|
+$1.14M
|
+111,600
|
+1%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$95.7M
|
+$5.93M
|
+579,481
|
+6%
|
|
|
11
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$68M
|
-$12.6M
|
-1,227,336
|
-15%
|
|
|
12
|
Janus Henderson Group
London,
|
$67.4M
|
+$21.1M
|
+2,065,621
|
+41%
|
|
|
13
|
|
$64M
|
+$30.1M
|
+2,946,955
|
+79%
|
|
|
14
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$60.8M
|
+$795K
|
+77,743
|
+1%
|
|
|
15
|
Jennison Associates
New York
|
$54.2M
|
-$927K
|
-90,644
|
-2%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$42.5M
|
-$2M
|
-195,109
|
-4%
|
|
|
17
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$29.3M
|
-$556K
|
-54,313
|
-2%
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$27.4M
|
+$15.4M
|
+1,501,395
|
+109%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$27M
|
-$1.27M
|
-124,285
|
-4%
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$26.5M
|
+$2.14M
|
+209,572
|
+8%
|
|
|
21
|
|
$26.4M
|
-$11.2M
|
-1,093,821
|
-28%
|
|
|
22
|
Novo Holdings A/S
Hellerup,
Denmark
|
$24.4M
|
+$5.75M
|
+562,331
|
+28%
|
|
|
23
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$23M
|
+$3.27M
|
+319,200
|
+15%
|
|
|
24
|
Boxer Capital
San Diego,
California
|
$22.2M
|
–
|
–
|
–
|
|
|
25
|
|
$20.9M
|
-$7.84M
|
-766,130
|
-26%
|
|
