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Edgewise Therapeutics

223 hedge funds and large institutions have $4.82B invested in Edgewise Therapeutics in 2026 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 83 increasing their positions, 72 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

94% more call options, than puts

Call options by funds: $17.6M | Put options by funds: $9.08M

58% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 26

29% more capital invested

Capital invested by funds: $3.72B → $4.82B (+$1.1B)

18% more funds holding in top 10

Funds holding in top 10: 1113 (+2)

15% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 72

4% more funds holding

Funds holding: 214223 (+9)

0.2% more ownership

Funds ownership: 110.5%110.7% (+0.2%)

Holders
223
Holders Change
+9
Holders Change %
+4.21%
% of All Funds
2.7%
Holding in Top 10
13
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+18.18%
% of All Funds
0.16%
New
41
Increased
83
Reduced
72
Closed
26
Calls
$17.6M
Puts
$9.08M
Net Calls
+$8.56M
Net Calls Change
+$900K
Name Holding Trade Value Shares
Change
Change in
Stake
HS
76
HighVista Strategies
Massachusetts
$3.7M -$32.2K -935 -1%
RhumbLine Advisers
77
RhumbLine Advisers
Massachusetts
$3.67M +$231K +6,692 +8%
ABG
78
Ally Bridge Group
New York
$3.38M -$2.68M -77,700 -48%
BFM
79
Boothbay Fund Management
New York
$3.36M +$2.85M +82,734 New
New York State Common Retirement Fund
80
New York State Common Retirement Fund
New York
$3.26M -$301K -8,740 -10%
Wells Fargo
81
Wells Fargo
California
$3.21M +$1.85M +53,654 +213%
Russell Investments Group
82
Russell Investments Group
United Kingdom
$3.16M +$2.45M +71,159 +1,082%
JFG
83
Jefferies Financial Group
New York
$2.9M +$2.46M +71,389 New
PAP
84
Persistent Asset Partners
Hong Kong
$2.82M +$2.05M +59,388 +591%
NAMI
85
Nomura Asset Management International
Pennsylvania
$2.64M -$85.8K -2,490 -4%
DekaBank Deutsche Girozentrale
86
DekaBank Deutsche Girozentrale
Germany
$2.52M
Citigroup
87
Citigroup
New York
$2.42M +$1.42M +41,046 +222%
Tudor Investment Corp
88
Tudor Investment Corp
Connecticut
$2.31M +$932K +27,045 +90%
State of Wisconsin Investment Board
89
State of Wisconsin Investment Board
Wisconsin
$2.31M +$828K +24,014 +73%
HWM
90
HighMark Wealth Management
Minnesota
$2.16M
Two Sigma Investments
91
Two Sigma Investments
New York
$2.01M -$44.8K -1,300 -3%
SEI Investments
92
SEI Investments
Pennsylvania
$1.93M -$53.1K -1,539 -3%
AG
93
Algert Global
California
$1.92M +$507K +14,720 +45%
XT
94
XTX Topco
Cayman Islands
$1.86M +$921K +26,724 +140%
Legal & General Group
95
Legal & General Group
United Kingdom
$1.82M +$74.2K +2,151 +5%
GCP
96
GSA Capital Partners
United Kingdom
$1.81M +$1.53M +44,466 New
BNP Paribas Financial Markets
97
BNP Paribas Financial Markets
France
$1.77M +$678K +19,676 +82%
MIM
98
MetLife Investment Management
New Jersey
$1.7M +$128K +3,720 +10%
Manulife (Manufacturers Life Insurance)
99
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.66M +$183K +5,307 +15%
Ensign Peak Advisors
100
Ensign Peak Advisors
Utah
$1.64M +$1.39M +40,379 New

EWTX Hedge Fund Activity: Q2 2026 in Review

223 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q2 2026, worth a combined $4.82B — up 29% from $3.72B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new EWTX positions and 26 closed out — a net gain of 15 holders — while 83 added to existing stakes and 72 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $154M. The largest seller was Baker Bros. Advisors, cutting an estimated $99.1M.

  • 223 institutional investors held Edgewise Therapeutics (EWTX) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $4.82B of Edgewise Therapeutics stock for Q2 2026, up 29% quarter-over-quarter.
  • 41 funds opened new Edgewise Therapeutics positions in Q2 2026 and 26 closed out, a net change of +15 holders.
  • The largest Edgewise Therapeutics buyer in Q2 2026 was Fidelity Investments, an estimated $154M added.
  • The largest Edgewise Therapeutics seller in Q2 2026 was Baker Bros. Advisors, an estimated $99.1M sold.

Based on aggregated 13F filings for Q2 2026.