DFTX

Definium Therapeutics

206 hedge funds and large institutions have $909M invested in Definium Therapeutics in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 91 increasing their positions, 31 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

63% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 30

16.66% more ownership

Funds ownership: 52.23%68.89% (+17%)

6% more funds holding

Funds holding: 194206 (+12)

Holders
206
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$23.4M
Puts
$10.8M
Net Calls
Net Calls Change

Top Buyers

1 +$61.9M
2 +$42.4M
3 +$29.5M
4
BlackRock
BlackRock
New York
+$28.9M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$16.2M

Top Sellers

1 -$15.2M
2 -$8.87M
3 -$7.08M
4
ABG
Ally Bridge Group
New York
-$4.26M
5
Citadel Advisors
Citadel Advisors
Florida
-$1.6M
Name Holding Trade Value Shares
Change
Change in
Stake
CIBC Private Wealth Group
176
CIBC Private Wealth Group
Georgia
$2.02K
AF
177
Allworth Financial
California
$1.98K
NA
178
NewEdge Advisors
Louisiana
$1.87K
Optiver Holding
179
Optiver Holding
Netherlands
$1.65K
HWM
180
HighMark Wealth Management
Minnesota
$1.34K
NS
181
NBC Securities
Alabama
$1.34K
SS
182
SBI Securities
Japan
$1.22K
RAM
183
Reflection Asset Management
South Carolina
$898
Federated Hermes
184
Federated Hermes
Pennsylvania
$897
AWM
185
Activest Wealth Management
Florida
$884
MASM
186
MH & Associates Securities Management
California
$884
KBFS
187
Kohmann Bosshard Financial Services
Ohio
$884
MCM
188
MAI Capital Management
Ohio
$791
TCM
189
Tradewinds Capital Management
Washington
$710
SS
190
Sunbelt Securities
Texas
$589
PMFA
191
Plante Moran Financial Advisors
Michigan
$482
FGAM
192
Financial Gravity Asset Management
Texas
$469
CAM
193
Chesapeake Asset Management
New York
$441
RF
194
Robbins Farley
New Hampshire
$375
PWPS
195
Pinnacle Wealth Planning Services
Ohio
$335
RIAS
196
Rachor Investment Advisory Services
Michigan
$335
CIAM
197
Caitong International Asset Management
Hong Kong
$201
CB
198
CNB Bank
Pennsylvania
$134
KFAS
199
Keating Financial Advisory Services
Kansas
$94
SAG
200
SageView Advisory Group
California
$81