DFTX

Definium Therapeutics

206 hedge funds and large institutions have $909M invested in Definium Therapeutics in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 91 increasing their positions, 31 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

63% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 30

16.66% more ownership

Funds ownership: 52.23%68.89% (+17%)

6% more funds holding

Funds holding: 194206 (+12)

Holders
206
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$23.4M
Puts
$10.8M
Net Calls
Net Calls Change

Top Buyers

1 +$61.9M
2 +$42.4M
3 +$29.5M
4
BlackRock
BlackRock
New York
+$28.9M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$16.2M

Top Sellers

1 -$15.2M
2 -$8.87M
3 -$7.08M
4
ABG
Ally Bridge Group
New York
-$4.26M
5
Citadel Advisors
Citadel Advisors
Florida
-$1.6M
Name Holding Trade Value Shares
Change
Change in
Stake
National Bank of Canada
151
National Bank of Canada
Quebec, Canada
$25K
QT
152
Quantbot Technologies
New York
$22.1K
TWC
153
TD Waterhouse Canada
Ontario, Canada
$20.5K
HNW
154
High Note Wealth
Minnesota
$20.1K
BNP Paribas Asset Management
155
BNP Paribas Asset Management
France
$18K
GI
156
GAMMA Investing
California
$13.8K
SPIA
157
Steward Partners Investment Advisory
New York
$13.4K
SHIM
158
Stone House Investment Management
Pennsylvania
$13.4K
UBS AM
159
UBS AM
Illinois
$12K
FHC
160
First Horizon Corporation
Tennessee
$11.3K
MPWT
161
MassMutual Private Wealth & Trust
Connecticut
$7.61K
GRP
162
Global Retirement Partners
California
$7.58K
LFG
163
Larson Financial Group
Missouri
$7.16K
SG
164
Sankala Group
Colorado
$6.82K
AUB
165
Atlantic Union Bankshares
Virginia
$6.7K
AAP
166
Arax Advisory Partners
Colorado
$6.41K
FFA
167
Farther Finance Advisors
California
$6.12K
NL
168
NVWM LLC
Pennsylvania
$5.57K
Rockefeller Capital Management
169
Rockefeller Capital Management
New York
$4.7K
RIL
170
Rothschild Investment LLC
Illinois
$3.84K
EWA
171
EverSource Wealth Advisors
Alabama
$3.4K
PA
172
Parallel Advisors
California
$3.12K
Daiwa Securities Group
173
Daiwa Securities Group
Japan
$3K
AEPWM
174
Atlantic Edge Private Wealth Management
Florida
$2.58K
Northwestern Mutual Wealth Management
175
Northwestern Mutual Wealth Management
Wisconsin
$2.48K