|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$85.3M
|
+$364K
|
+30,097
|
+0.6%
|
|
|
2
|
Canaan Partners IX
Menlo Park,
California
|
$66.6M
|
–
|
–
|
–
|
|
|
3
|
Putnam Investments
Boston,
Massachusetts
|
$21.5M
|
+$12.6M
|
+1,044,801
|
+321%
|
|
|
4
|
Deerfield Management
New York
|
$14.8M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$12.3M
|
+$5M
|
+413,124
|
+111%
|
|
|
6
|
Tekla Capital Management
Boston,
Massachusetts
|
$11.9M
|
–
|
–
|
–
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$11.2M
|
-$232K
|
-19,207
|
-3%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$9.28M
|
-$173K
|
-14,325
|
-2%
|
|
|
9
|
VHCP Management II
New York
|
$9.06M
|
–
|
–
|
–
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
$8.75M
|
+$370K
|
+30,603
|
+6%
|
|
|
11
|
Cormorant Asset Management
Boston,
Massachusetts
|
$5.83M
|
–
|
–
|
–
|
|
|
12
|
Franklin Resources
San Mateo,
California
|
$5.23M
|
–
|
–
|
–
|
|
|
13
|
BlackRock Advisors
Wilmington,
Delaware
|
$5.23M
|
-$2.53M
|
-209,041
|
-39%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$4.25M
|
+$198K
|
+16,386
|
+6%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$3.39M
|
+$1.41M
|
+116,552
|
+117%
|
|
|
16
|
Private Advisor Group
Morristown,
New Jersey
|
$3.29M
|
-$90.8K
|
-7,500
|
-3%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$2.83M
|
+$1.27M
|
+104,547
|
+137%
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$2.71M
|
+$87.9K
|
+7,264
|
+4%
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
$2.51M
|
–
|
–
|
–
|
|
|
20
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.43M
|
+$1.06M
|
+88,000
|
+131%
|
|
|
21
|
Eventide Asset Management
Boston,
Massachusetts
|
$2.35M
|
–
|
–
|
–
|
|
|
22
|
Montecito Bank & Trust
Santa Barbara,
California
|
$2.3M
|
–
|
–
|
–
|
|
|
23
|
|
$2M
|
-$1.29M
|
-106,679
|
-46%
|
|
|
24
|
Bank of New York Mellon
New York
|
$1.32M
|
+$150K
|
+12,427
|
+17%
|
|
|
25
|
BlackRock Investment Management
Wilmington,
Delaware
|
$1.2M
|
-$1.58K
|
-131
|
-0.2%
|
|
