|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$465M
|
+$157M
|
+2,801,736
|
+45%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$456M
|
+$250M
|
+4,472,316
|
+100%
|
|
|
3
|
|
$384M
|
+$54M
|
+965,251
|
+15%
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$355M
|
+$139M
|
+2,490,876
|
+56%
|
|
|
5
|
Driehaus Capital Management
Chicago,
Illinois
|
$314M
|
+$14.3M
|
+255,766
|
+4%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$277M
|
+$26.3M
|
+469,748
|
+9%
|
|
|
7
|
EcoR1 Capital
San Francisco,
California
|
$219M
|
–
|
–
|
–
|
|
|
8
|
Farallon Capital Management
San Francisco,
California
|
$208M
|
+$163M
|
+2,913,098
|
+251%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$153M
|
+$8.52M
|
+152,354
|
+5%
|
|
|
10
|
Janus Henderson Group
London,
|
$143M
|
+$20.5M
|
+365,991
|
+15%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$143M
|
+$27.3M
|
+488,296
|
+21%
|
|
|
12
|
Jennison Associates
New York
|
$138M
|
-$4.77M
|
-85,263
|
-3%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$107M
|
+$14M
|
+250,708
|
+14%
|
|
|
14
|
Paradigm Biocapital Advisors
New York
|
$97.7M
|
-$33.9M
|
-605,925
|
-24%
|
|
|
15
|
Siren LLC
Greenwich,
Connecticut
|
$82.3M
|
+$16.8M
|
+300,000
|
+23%
|
|
|
16
|
Franklin Resources
San Mateo,
California
|
$81.4M
|
+$11.3M
|
+201,556
|
+14%
|
|
|
17
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$51.3M
|
-$3.67M
|
-65,650
|
-6%
|
|
|
18
|
Cormorant Asset Management
Boston,
Massachusetts
|
$51.1M
|
-$5.59M
|
-100,000
|
-9%
|
|
|
19
|
|
$51.1M
|
-$2.86M
|
-51,055
|
-5%
|
|
|
20
|
Novo Holdings A/S
Hellerup,
Denmark
|
$49.1M
|
-$2.23M
|
-39,785
|
-4%
|
|
|
21
|
First Light Asset Management
Edina,
Minnesota
|
$45.3M
|
-$3.25M
|
-58,158
|
-6%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$45M
|
+$8.35M
|
+149,298
|
+20%
|
|
|
23
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$43.5M
|
+$922K
|
+16,488
|
+2%
|
|
|
24
|
Pictet Asset Management
Carouge,
Switzerland
|
$43.4M
|
-$3.36M
|
-60,099
|
-7%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$38.8M
|
+$5.8M
|
+103,708
|
+16%
|
|
