|
1
|
|
$335M
|
+$16.5M
|
+319,571
|
+5%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$321M
|
+$91.5M
|
+1,773,177
|
+39%
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$301M
|
-$11.7M
|
-226,925
|
-4%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$253M
|
+$27.8M
|
+538,301
|
+12%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$228M
|
-$8.29M
|
-160,722
|
-3%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$228M
|
+$18.5M
|
+358,975
|
+9%
|
|
|
7
|
EcoR1 Capital
San Francisco,
California
|
$219M
|
+$6.85M
|
+132,745
|
+3%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$145M
|
+$1.32M
|
+25,561
|
+0.9%
|
|
|
9
|
Jennison Associates
New York
|
$143M
|
+$695K
|
+13,470
|
+0.5%
|
|
|
10
|
Paradigm Biocapital Advisors
New York
|
$129M
|
+$175K
|
+3,384
|
+0.1%
|
|
|
11
|
Janus Henderson Group
London,
|
$124M
|
-$1.35M
|
-26,211
|
-1%
|
|
|
12
|
Point72 Asset Management
Stamford,
Connecticut
|
$118M
|
-$24.8M
|
-480,213
|
-17%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$94.5M
|
+$8.75M
|
+169,746
|
+10%
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$73.8M
|
+$27.3M
|
+528,688
|
+61%
|
|
|
15
|
Siren LLC
Greenwich,
Connecticut
|
$66.9M
|
+$67.5M
|
+1,309,652
|
New
|
|
|
16
|
Farallon Capital Management
San Francisco,
California
|
$59.4M
|
+$34.3M
|
+665,000
|
+134%
|
|
|
17
|
Cormorant Asset Management
Boston,
Massachusetts
|
$56.2M
|
-$12.9M
|
-250,000
|
-19%
|
|
|
18
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$54.6M
|
-$14.4M
|
-278,678
|
-21%
|
|
|
19
|
|
$53.7M
|
-$11.9M
|
-230,745
|
-18%
|
|
|
20
|
Novo Holdings A/S
Hellerup,
Denmark
|
$51.1M
|
–
|
–
|
–
|
|
|
21
|
First Light Asset Management
Edina,
Minnesota
|
$48.2M
|
-$13.2M
|
-256,897
|
-21%
|
|
|
22
|
Pictet Asset Management
Carouge,
Switzerland
|
$46.4M
|
+$31.3M
|
+607,281
|
+202%
|
|
|
23
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$42.7M
|
+$21.9M
|
+424,570
|
+103%
|
|
|
24
|
|
$40.2M
|
+$7.11M
|
+137,838
|
+21%
|
|
|
25
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$38.1M
|
-$7.31M
|
-141,803
|
-16%
|
|
