|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$82.3M
|
+$16.6M
|
+675,749
|
+23%
|
|
|
2
|
Vivo Capital
Palo Alto,
California
|
$76.8M
|
-$10.2M
|
-417,000
|
-11%
|
|
|
3
|
Perceptive Advisors
New York
|
$58.9M
|
–
|
–
|
–
|
|
|
4
|
|
$43.6M
|
–
|
–
|
–
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$42.7M
|
–
|
–
|
–
|
|
|
6
|
|
$17.7M
|
+$2.08M
|
+84,802
|
+12%
|
|
|
7
|
Janus Henderson Group
London,
|
$11.1M
|
-$1.02M
|
-41,459
|
-8%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$11.1M
|
+$1.28M
|
+52,134
|
+12%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$10.3M
|
+$4.41M
|
+179,489
|
+66%
|
|
|
10
|
Eventide Asset Management
Boston,
Massachusetts
|
$8.74M
|
+$6.41M
|
+260,775
|
+212%
|
|
|
11
|
Adage Capital Partners
Boston,
Massachusetts
|
$6.6M
|
–
|
–
|
–
|
|
|
12
|
|
$4.55M
|
–
|
–
|
–
|
|
|
13
|
New Leaf Venture Partners
New York
|
$3.82M
|
–
|
–
|
–
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$3.07M
|
–
|
–
|
–
|
|
|
15
|
Baker Bros. Advisors
New York
|
$2.99M
|
–
|
–
|
–
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$2.4M
|
+$55.3K
|
+2,251
|
+2%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$2.38M
|
+$678K
|
+27,602
|
+36%
|
|
|
18
|
Emory University
Atlanta,
Georgia
|
$2.21M
|
+$273K
|
+11,091
|
+13%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$2.05M
|
+$357K
|
+14,539
|
+19%
|
|
|
20
|
Opaleye Management
Boston,
Massachusetts
|
$1.66M
|
+$1.79M
|
+73,000
|
New
|
|
|
21
|
Victory Capital Management
San Antonio,
Texas
|
$1.22M
|
-$14.5K
|
-590
|
-1%
|
|
|
22
|
UBS Group
Zurich,
Switzerland
|
$988K
|
+$1.05M
|
+42,821
|
+7,197%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$916K
|
+$156K
|
+6,343
|
+19%
|
|
|
24
|
Marshall Wace
London,
United Kingdom
|
$775K
|
+$837K
|
+34,062
|
New
|
|
|
25
|
Bank of America
Charlotte,
North Carolina
|
$682K
|
+$590K
|
+24,012
|
+405%
|
|
