|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$90.5M
|
+$159K
|
+6,413
|
+0.2%
|
|
|
2
|
Vivo Capital
Palo Alto,
California
|
$84.4M
|
–
|
–
|
–
|
|
|
3
|
Perceptive Advisors
New York
|
$64.7M
|
–
|
–
|
–
|
|
|
4
|
|
$51M
|
+$3.1M
|
+125,000
|
+7%
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$46.9M
|
–
|
–
|
–
|
|
|
6
|
|
$23.3M
|
+$3.82M
|
+154,450
|
+20%
|
|
|
7
|
Eventide Asset Management
Boston,
Massachusetts
|
$20.1M
|
+$10.4M
|
+419,839
|
+109%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$12.6M
|
+$1.3M
|
+52,327
|
+12%
|
|
|
9
|
Janus Henderson Group
London,
|
$12.5M
|
+$277K
|
+11,175
|
+2%
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$12.3M
|
+$4.95M
|
+200,000
|
+69%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$12.2M
|
+$44.2K
|
+1,786
|
+0.4%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$5.09M
|
+$2.43M
|
+98,229
|
+93%
|
|
|
13
|
|
$4.53M
|
+$4.13M
|
+166,599
|
+1,158%
|
|
|
14
|
New Leaf Venture Partners
New York
|
$4.19M
|
–
|
–
|
–
|
|
|
15
|
Novo Holdings A/S
Hellerup,
Denmark
|
$3.38M
|
–
|
–
|
–
|
|
|
16
|
Baker Bros. Advisors
New York
|
$3.33M
|
+$43K
|
+1,735
|
+1%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$2.99M
|
+$727K
|
+29,343
|
+33%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$2.69M
|
+$84.6K
|
+3,415
|
+3%
|
|
|
19
|
Polar Capital
London,
United Kingdom
|
$2.5M
|
+$2.48M
|
+100,000
|
New
|
|
|
20
|
Marshall Wace North America
New York
|
$1.85M
|
+$1.78M
|
+72,014
|
+3,768%
|
|
|
21
|
Victory Capital Management
San Antonio,
Texas
|
$1.74M
|
+$404K
|
+16,300
|
+31%
|
|
|
22
|
ALPS Advisors
Denver,
Colorado
|
$1.26M
|
+$1.25M
|
+50,525
|
New
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$1.15M
|
+$147K
|
+5,929
|
+15%
|
|
|
24
|
Bank of New York Mellon
New York
|
$964K
|
+$312K
|
+12,608
|
+49%
|
|
|
25
|
Opaleye Management
Boston,
Massachusetts
|
$900K
|
-$916K
|
-37,000
|
-51%
|
|
