|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$91.2M
|
+$139K
|
+7,320
|
+0.2%
|
|
|
2
|
Perceptive Advisors
New York
|
$64.9M
|
–
|
–
|
–
|
|
|
3
|
5AM Venture Management
San Francisco,
California
|
$59.3M
|
+$45M
|
+2,362,286
|
New
|
|
|
4
|
|
$51.2M
|
–
|
–
|
–
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$47M
|
–
|
–
|
–
|
|
|
6
|
Eventide Asset Management
Boston,
Massachusetts
|
$23.8M
|
–
|
–
|
–
|
|
|
7
|
|
$18.4M
|
-$4.42M
|
-231,947
|
-24%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$12.6M
|
-$1.9K
|
-100
|
-0%
|
|
|
9
|
Janus Henderson Group
London,
|
$12.3M
|
-$148K
|
-7,788
|
-2%
|
|
|
10
|
Opaleye Management
Boston,
Massachusetts
|
$6.68M
|
+$1.13M
|
+59,100
|
+29%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$5.68M
|
+$387K
|
+20,305
|
+10%
|
|
|
12
|
Burrage Capital Management
Boston,
Massachusetts
|
$5.16M
|
+$3.92M
|
+205,726
|
New
|
|
|
13
|
Polar Capital
London,
United Kingdom
|
$5.02M
|
+$2.09M
|
+109,618
|
+121%
|
|
|
14
|
Victory Capital Management
San Antonio,
Texas
|
$4.9M
|
-$364K
|
-19,130
|
-9%
|
|
|
15
|
Baker Bros. Advisors
New York
|
$4.39M
|
–
|
–
|
–
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$3.73M
|
+$244K
|
+12,793
|
+9%
|
|
|
17
|
New Leaf Venture Partners
New York
|
$3.54M
|
–
|
–
|
–
|
|
|
18
|
Novo Holdings A/S
Hellerup,
Denmark
|
$3.39M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$3.22M
|
+$128K
|
+6,731
|
+6%
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$1.33M
|
+$37K
|
+1,944
|
+4%
|
|
|
21
|
ALPS Advisors
Denver,
Colorado
|
$1.23M
|
+$18.2K
|
+955
|
+2%
|
|
|
22
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$906K
|
-$308K
|
-16,175
|
-31%
|
|
|
23
|
Bank of New York Mellon
New York
|
$899K
|
+$22.5K
|
+1,183
|
+3%
|
|
|
24
|
Point72 Asset Management
Stamford,
Connecticut
|
$850K
|
-$1.87M
|
-98,135
|
-74%
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$709K
|
-$5.69K
|
-299
|
-1%
|
|
