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BPMC

Blueprint Medicines
BPMC

Delisted

BPMC was delisted on the 17th of July, 2025.

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5 hedge funds and large institutions have $2.58M invested in Blueprint Medicines in 2025 Q3 according to their latest regulatory filings, with 0 funds opening new positions, 1 increasing their positions, 3 reducing their positions, and 344 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% less repeat investments, than reductions

Existing positions increased: 1 | Existing positions reduced: 3

99% less funds holding

Funds holding: 354 → 5 (-349)

99.54% less ownership

Funds ownership: 99.58% → 0.04% (-100%)

100% less capital invested

Capital invested by funds: $8.24B → $2.58M (-$8.24B)

100% less funds holding in top 10

Funds holding in top 10: 29 → 0 (-29)

100% less first-time investments, than exits

New positions opened: 0 | Existing positions closed: 344

Holders
5
Holders Change
-349
Holders Change %
-98.59%
% of All Funds
0.07%
Holding in Top 10
–
Holding in Top 10 Change
-29
Holding in Top 10 Change %
-100%
% of All Funds
–
New
–
Increased
1
Reduced
3
Closed
344
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
IA
IFP Advisors
Florida
+$2.06K

Top Sellers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
-$822M
2
BlackRock
BlackRock
New York
-$784M
3
PCM
Pentwater Capital Management
Florida
-$500M
4
State Street
State Street
Massachusetts
-$286M
5
UBS Group
UBS Group
Switzerland
-$278M
Name Holding Trade Value Shares
Change 		Change in
Stake
TAL
51
TIG Advisors LLC
New York
– -$39.1M -305,097 Closed
Millennium Management
52
Millennium Management
New York
– -$37.9M -295,879 Closed
SC
53
Slotnik Capital
Texas
– -$37.5M -292,694 Closed
BG
54
Bellevue Group
Switzerland
– -$36.5M -284,900 Closed
Janus Henderson Group
55
Janus Henderson Group
United Kingdom
– -$34.5M -268,928 Closed
CCM
56
Cinctive Capital Management
New York
– -$34M -265,000 Closed
NHAS
57
Novo Holdings A/S
Denmark
– -$34M -264,956 Closed
PAMP
58
Polar Asset Management Partners
Ontario, Canada
– -$33.7M -262,964 Closed
AAA
59
Affinity Asset Advisors
New York
– -$32M -250,000 Closed
SFM
60
Soros Fund Management
New York
– -$32M -250,000 Closed
KC
61
Kryger Capital
United Kingdom
– -$31.8M -248,219 Closed
TC
62
Trium Capital
United Kingdom
– -$30.8M -240,099 Closed
Bank of New York Mellon
63
Bank of New York Mellon
New York
– -$29.2M -227,843 Closed
UBS AM
64
UBS AM
Illinois
– -$27.7M -215,946 Closed
Jane Street
65
Jane Street
New York
– -$27.5M -214,394 Closed
GF
66
Gabelli Funds
New York
– -$27.1M -211,169 Closed
SGCM
67
Sand Grove Capital Management
United Kingdom
– -$27.1M -211,124 Closed
HCM
68
Highbridge Capital Management
New York
– -$24.3M -189,822 Closed
Deutsche Bank
69
Deutsche Bank
Germany
– -$24.3M -189,250 Closed
RSCM
70
Rock Springs Capital Management
Maryland
– -$23.8M -185,500 Closed
OBAM
71
ODDO BHF Asset Management
France
– -$23.7M -185,000 Closed
Susquehanna International Group
72
Susquehanna International Group
Pennsylvania
– -$23.6M -184,115 Closed
GCIA
73
Gabelli & Co Investment Advisers
New York
– -$23.5M -183,374 Closed
Franklin Resources
74
Franklin Resources
California
– -$22.2M -173,510 Closed
PMAM
75
Picton Mahoney Asset Management
Ontario, Canada
– -$21.8M -170,000 Closed
1 2
3
4 5

BPMC Hedge Fund Activity: Q3 2025 in Review

5 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q3 2025, worth a combined $2.58M — down 100% from $8.24B a quarter earlier.

Sellers outnumbered buyers: 344 funds closed out of BPMC and 0 opened new positions — a net loss of 344 holders — while 3 trimmed existing stakes and 1 added.

The largest buyer was IFP Advisors, adding an estimated $2.06K. The largest seller was Vanguard Group, exiting entirely with an estimated $822M sold.

  • 5 institutional investors held Blueprint Medicines (BPMC) as of Q3 2025, down from 354 in Q2 2025.
  • Funds reported $2.58M of Blueprint Medicines stock for Q3 2025, down 100% quarter-over-quarter.
  • 0 funds opened new Blueprint Medicines positions in Q3 2025 and 344 closed out, a net change of -344 holders.
  • The largest Blueprint Medicines buyer in Q3 2025 was IFP Advisors, an estimated $2.06K added.
  • The largest Blueprint Medicines seller in Q3 2025 was Vanguard Group, an estimated $822M sold.

Based on aggregated 13F filings for Q3 2025.