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BPMC

Blueprint Medicines
BPMC

Delisted

BPMC was delisted on the 17th of July, 2025.

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263 hedge funds and large institutions have $5.69B invested in Blueprint Medicines in 2021 Q1 according to their latest regulatory filings, with 35 funds opening new positions, 103 increasing their positions, 93 reducing their positions, and 46 closing their positions.

New
Increased
Maintained
Reduced
Closed

11% more repeat investments, than reductions

Existing positions increased: 103 | Existing positions reduced: 93

0% more funds holding in top 10

Funds holding in top 10: 7 → 7 (0)

1.73% less ownership

Funds ownership: 102.68% → 100.96% (-1.7%)

5% less funds holding

Funds holding: 278 → 263 (-15)

12% less capital invested

Capital invested by funds: $6.46B → $5.69B (-$770M)

24% less first-time investments, than exits

New positions opened: 35 | Existing positions closed: 46

51% less call options, than puts

Call options by funds: $8.55M | Put options by funds: $17.3M

Holders
263
Holders Change
-15
Holders Change %
-5.4%
% of All Funds
4.62%
Holding in Top 10
7
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.12%
New
35
Increased
103
Reduced
93
Closed
46
Calls
$8.55M
Puts
$17.3M
Net Calls
-$8.74M
Net Calls Change
+$24.4M

Top Buyers

Rank Fund Capital Flow
1
FCM
Farallon Capital Management
California
+$69.4M
2
Jennison Associates
Jennison Associates
New York
+$39.1M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$36.1M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$32.7M
5
APM
Avidity Partners Management
Texas
+$30.6M

Top Sellers

Rank Fund Capital Flow
1
HA
HHLR Advisors
Cayman Islands
-$51.1M
2
PAMU
Pictet Asset Management (UK)
United Kingdom
-$22.2M
3
EVM
Eaton Vance Management
Massachusetts
-$18.6M
4
Morgan Stanley
Morgan Stanley
New York
-$17.2M
5
SAM
Sectoral Asset Management
Quebec, Canada
-$15.3M
Name Holding Trade Value Shares
Change 		Change in
Stake
Viking Global Investors
51
Viking Global Investors
Connecticut
$20.7M -$5.95M -59,631 -22%
DM
52
Deerfield Management
New York
$20.3M +$20.9M +209,000 New
DCM
53
DAFNA Capital Management
California
$20.2M +$99.8K +1,000 +0.5%
Renaissance Technologies
54
Renaissance Technologies
New York
$19.4M -$8.24M -82,500 -29%
NHAS
55
Novo Holdings A/S
Denmark
$19.2M – – –
Prudential Financial
56
Prudential Financial
New Jersey
$18.6M +$4.19M +41,948 +28%
PCM
57
Peregrine Capital Management
Minnesota
$14.7M -$2.11M -21,086 -12%
VOYA Investment Management
58
VOYA Investment Management
Georgia
$14.4M -$2.12M -21,257 -13%
Millennium Management
59
Millennium Management
New York
$13.4M +$12.2M +122,680 +807%
EHI
60
Eagle Health Investments
Connecticut
$12.9M +$7.1M +71,103 +115%
DCM
61
Driehaus Capital Management
Illinois
$12.8M +$444K +4,450 +4%
California Public Employees Retirement System
62
California Public Employees Retirement System
California
$12.7M +$610K +6,112 +5%
TCM
63
Tekla Capital Management
Massachusetts
$11.9M – – –
Swiss National Bank
64
Swiss National Bank
Switzerland
$11.8M +$230K +2,300 +2%
IHAM
65
Integral Health Asset Management
New York
$11.4M +$3.24M +32,500 +38%
MCM
66
Moore Capital Management
New York
$11.4M -$8.84M -88,543 -43%
Axa
67
Axa
France
$10.2M +$195K +1,958 +2%
Wells Fargo
68
Wells Fargo
California
$9M +$3.06M +30,684 +50%
WP
69
Woodline Partners
California
$8.64M +$8.88M +88,906 New
California State Teachers Retirement System (CalSTRS)
70
California State Teachers Retirement System (CalSTRS)
California
$8.62M -$28.2K -282 -0.3%
PI
71
Putnam Investments
Massachusetts
$8.62M +$8.86M +88,700 New
TD Asset Management
72
TD Asset Management
Ontario, Canada
$7.33M +$930K +9,315 +14%
SEI Investments
73
SEI Investments
Pennsylvania
$7.33M +$1.5M +15,073 +26%
Federated Hermes
74
Federated Hermes
Pennsylvania
$7.31M -$4.12M -41,267 -35%
State of Wisconsin Investment Board
75
State of Wisconsin Investment Board
Wisconsin
$7.24M -$290K -2,900 -4%
1 2
3
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BPMC Hedge Fund Activity: Q1 2021 in Review

263 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q1 2021, worth a combined $5.69B — down 12% from $6.46B a quarter earlier.

Sellers outnumbered buyers: 46 funds closed out of BPMC and 35 opened new positions — a net loss of 11 holders — while 93 trimmed existing stakes and 103 added.

The largest buyer was Farallon Capital Management, opening a new position worth an estimated $69.4M. The largest seller was HHLR Advisors, cutting an estimated $51.1M.

  • 263 institutional investors held Blueprint Medicines (BPMC) as of Q1 2021, down from 278 in Q4 2020.
  • Funds reported $5.69B of Blueprint Medicines stock for Q1 2021, down 12% quarter-over-quarter.
  • 35 funds opened new Blueprint Medicines positions in Q1 2021 and 46 closed out, a net change of -11 holders.
  • The largest Blueprint Medicines buyer in Q1 2021 was Farallon Capital Management, an estimated $69.4M added.
  • The largest Blueprint Medicines seller in Q1 2021 was HHLR Advisors, an estimated $51.1M sold.

Based on aggregated 13F filings for Q1 2021.