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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

248 hedge funds and large institutions have $3.74B invested in Blueprint Medicines in 2022 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 85 increasing their positions, 91 reducing their positions, and 64 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more call options, than puts

Call options by funds: $11.6M | Put options by funds: $7.29M

0.66% more ownership

Funds ownership: 100.38%101.04% (+0.66%)

7% less repeat investments, than reductions

Existing positions increased: 85 | Existing positions reduced: 91

11% less funds holding

Funds holding: 280248 (-32)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

41% less capital invested

Capital invested by funds: $6.29B → $3.74B (-$2.55B)

47% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 64

Holders
248
Holders Change
-32
Holders Change %
-11.43%
% of All Funds
3.91%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.08%
New
34
Increased
85
Reduced
91
Closed
64
Calls
$11.6M
Puts
$7.29M
Net Calls
+$4.33M
Net Calls Change
+$6.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Charles Schwab
26
Charles Schwab
California
$28.6M +$707K +9,854 +2%
Loomis, Sayles & Company
27
Loomis, Sayles & Company
Massachusetts
$28M +$4.23M +58,923 +16%
Citadel Advisors
28
Citadel Advisors
Florida
$27.8M +$24.3M +338,425 +351%
Franklin Resources
29
Franklin Resources
California
$26.4M -$501K -6,981 -2%
Fisher Asset Management
30
Fisher Asset Management
Washington
$25.4M -$159K -2,218 -0.6%
Bank of America
31
Bank of America
North Carolina
$23.4M +$5.85M +81,501 +29%
EAM
32
Eagle Asset Management
Florida
$22.8M -$1.98M -27,598 -7%
First Manhattan
33
First Manhattan
New York
$20.2M
Goldman Sachs
34
Goldman Sachs
New York
$19.6M -$6.73M -93,695 -23%
APM
35
Avidity Partners Management
Texas
$18.6M -$50.5M -703,816 -71%
Assenagon Asset Management
36
Assenagon Asset Management
Luxembourg
$17.5M +$15.5M +216,374 +371%
Bank of New York Mellon
37
Bank of New York Mellon
New York
$15.8M -$28.4M -395,996 -62%
DCM
38
DAFNA Capital Management
California
$15.7M +$2.83M +39,369 +19%
TCM
39
TimesSquare Capital Management
New York
$15.6M -$82.1M -1,143,431 -82%
UBS AM
40
UBS AM
Illinois
$15.3M +$385K +5,369 +2%
N
41
Nuveen
North Carolina
$14.6M -$9.75M -135,898 -37%
NHAS
42
Novo Holdings A/S
Denmark
$14.5M +$2.19M +30,526 +15%
Morgan Stanley
43
Morgan Stanley
New York
$14.3M +$6.12M +85,298 +61%
Deutsche Bank
44
Deutsche Bank
Germany
$12.7M -$245K -3,418 -2%
CS
45
Candriam SCA
Luxembourg
$12.1M -$11.7M -162,802 -46%
NI
46
Nextech Invest
Switzerland
$12M +$13.5M +188,228 New
Marshall Wace
47
Marshall Wace
United Kingdom
$11.9M -$54.8M -764,082 -80%
PAM
48
Panagora Asset Management
Massachusetts
$11.5M +$278K +3,867 +2%
SBH
49
Segall Bryant & Hamill
Illinois
$11.2M +$8.37M +116,602 +198%
EHI
50
Eagle Health Investments
Connecticut
$10.9M -$1.59M -22,088 -11%

BPMC Hedge Fund Activity: Q1 2022 in Review

248 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q1 2022, worth a combined $3.74B — down 41% from $6.29B a quarter earlier.

Sellers outnumbered buyers: 64 funds closed out of BPMC and 34 opened new positions — a net loss of 30 holders — while 91 trimmed existing stakes and 85 added.

The largest buyer was Fidelity Investments, adding an estimated $214M. The largest seller was TimesSquare Capital Management, cutting an estimated $82.1M.

  • 248 institutional investors held Blueprint Medicines (BPMC) as of Q1 2022, down from 280 in Q4 2021.
  • Funds reported $3.74B of Blueprint Medicines stock for Q1 2022, down 41% quarter-over-quarter.
  • 34 funds opened new Blueprint Medicines positions in Q1 2022 and 64 closed out, a net change of -30 holders.
  • The largest Blueprint Medicines buyer in Q1 2022 was Fidelity Investments, an estimated $214M added.
  • The largest Blueprint Medicines seller in Q1 2022 was TimesSquare Capital Management, an estimated $82.1M sold.

Based on aggregated 13F filings for Q1 2022.