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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

288 hedge funds and large institutions have $6.12B invested in Blueprint Medicines in 2021 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 99 increasing their positions, 94 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

95% more call options, than puts

Call options by funds: $36.7M | Put options by funds: $18.9M

60% more funds holding in top 10

Funds holding in top 10: 58 (+3)

38% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 29

19% more capital invested

Capital invested by funds: $5.14B → $6.12B (+$981M)

2% more funds holding

Funds holding: 281288 (+7)

1.59% more ownership

Funds ownership: 100.24%101.83% (+1.6%)

5% more repeat investments, than reductions

Existing positions increased: 99 | Existing positions reduced: 94

Holders
288
Holders Change
+7
Holders Change %
+2.49%
% of All Funds
5.04%
Holding in Top 10
8
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+60%
% of All Funds
0.14%
New
40
Increased
99
Reduced
94
Closed
29
Calls
$36.7M
Puts
$18.9M
Net Calls
+$17.8M
Net Calls Change
+$23.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Goldman Sachs
26
Goldman Sachs
New York
$63M +$5.84M +62,685 +11%
ACM
27
Aquilo Capital Management
California
$53.6M +$6.81M +73,161 +16%
Franklin Resources
28
Franklin Resources
California
$50.6M -$1.74M -18,734 -4%
Charles Schwab
29
Charles Schwab
California
$47.9M +$337K +3,616 +0.8%
Deutsche Bank
30
Deutsche Bank
Germany
$44M -$359K -3,860 -0.9%
BC
31
Boxer Capital
California
$43.7M +$39.6M +425,000 New
Lord, Abbett & Co
32
Lord, Abbett & Co
New Jersey
$43.7M -$1.25M -13,442 -3%
Point72 Asset Management
33
Point72 Asset Management
Connecticut
$43M +$14.7M +157,356 +60%
MWNA
34
Marshall Wace North America
New York
$42.1M +$36M +386,792 +1,726%
EAM
35
Eagle Asset Management
Florida
$40.8M -$5.18M -55,656 -12%
Jennison Associates
36
Jennison Associates
New York
$40.7M -$780K -8,371 -2%
Loomis, Sayles & Company
37
Loomis, Sayles & Company
Massachusetts
$40M -$562K -6,040 -2%
N
38
Nuveen
North Carolina
$37.1M +$582K +6,248 +2%
EAM
39
Eventide Asset Management
Massachusetts
$36.6M -$9.84M -105,712 -23%
First Manhattan
40
First Manhattan
New York
$32.7M
Fisher Asset Management
41
Fisher Asset Management
Washington
$32.5M +$29.4M +315,658 New
CS
42
Candriam SCA
Luxembourg
$32.2M
Dimensional Fund Advisors
43
Dimensional Fund Advisors
Texas
$28.9M +$20.2M +216,778 +337%
EVM
44
Eaton Vance Management
Massachusetts
$27.1M +$60.8K +653 +0.2%
Bank of America
45
Bank of America
North Carolina
$26.8M +$241K +2,585 +1%
UBS AM
46
UBS AM
Illinois
$26.8M -$1.98M -21,288 -8%
Assenagon Asset Management
47
Assenagon Asset Management
Luxembourg
$25.3M -$1.5M -16,108 -6%
EMFAT
48
Emerald Mutual Fund Advisers Trust
Pennsylvania
$25.2M
EA
49
Emerald Advisers
Pennsylvania
$24M +$668K +7,173 +3%
D.E. Shaw & Co
50
D.E. Shaw & Co
New York
$21.3M -$5.96M -63,948 -24%

BPMC Hedge Fund Activity: Q3 2021 in Review

288 of the 5,712 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q3 2021, worth a combined $6.12B — up 19% from $5.14B a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new BPMC positions and 29 closed out — a net gain of 11 holders — while 99 added to existing stakes and 94 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $110M. The largest seller was Fidelity Investments, cutting an estimated $96.7M.

  • 288 institutional investors held Blueprint Medicines (BPMC) as of Q3 2021, up from 281 in Q2 2021.
  • Funds reported $6.12B of Blueprint Medicines stock for Q3 2021, up 19% quarter-over-quarter.
  • 40 funds opened new Blueprint Medicines positions in Q3 2021 and 29 closed out, a net change of +11 holders.
  • The largest Blueprint Medicines buyer in Q3 2021 was Wellington Management Group, an estimated $110M added.
  • The largest Blueprint Medicines seller in Q3 2021 was Fidelity Investments, an estimated $96.7M sold.

Based on aggregated 13F filings for Q3 2021.