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Arrowhead Research

265 hedge funds and large institutions have $1.34B invested in Arrowhead Research in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 89 increasing their positions, 82 reducing their positions, and 46 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 82

7% less first-time investments, than exits

New positions opened: 43 | Existing positions closed: 46

1% less funds holding

Funds holding: 269265 (-4)

3.44% less ownership

Funds ownership: 80.16%76.72% (-3.4%)

25% less call options, than puts

Call options by funds: $4.66M | Put options by funds: $6.24M

28% less capital invested

Capital invested by funds: $1.88B → $1.34B (-$532M)

Holders
265
Holders Change
-4
Holders Change %
-1.49%
% of All Funds
3.55%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
43
Increased
89
Reduced
82
Closed
46
Calls
$4.66M
Puts
$6.24M
Net Calls
-$1.58M
Net Calls Change
-$3.28M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
101
Janus Henderson Group
United Kingdom
$689K
GC
102
Guggenheim Capital
Illinois
$679K +$125K +6,850 +15%
SSA
103
Schonfeld Strategic Advisors
New York
$670K -$10.5M -579,594 -92%
Wellington Management Group
104
Wellington Management Group
Massachusetts
$670K -$50.6K -2,782 -5%
EAM
105
Erste Asset Management
Austria
$650K
ETC
106
Exchange Traded Concepts
Oklahoma
$627K +$216K +11,879 +32%
Ensign Peak Advisors
107
Ensign Peak Advisors
Utah
$618K
YCM
108
Yousif Capital Management
Michigan
$603K +$42.8K +2,353 +5%
OTPPB
109
Ontario Teachers' Pension Plan Board
Ontario, Canada
$583K +$832K +45,769 New
Victory Capital Management
110
Victory Capital Management
Texas
$577K +$410K +22,546 +99%
Royal Bank of Canada
111
Royal Bank of Canada
Ontario, Canada
$576K +$191K +10,496 +30%
PA
112
Profund Advisors
Maryland
$557K +$241K +13,250 +43%
Comerica Bank
113
Comerica Bank
Texas
$539K +$117K +6,422 +18%
Handelsbanken Fonder
114
Handelsbanken Fonder
Sweden
$525K
DekaBank Deutsche Girozentrale
115
DekaBank Deutsche Girozentrale
Germany
$518K
EGM
116
Engineers Gate Manager
New York
$517K -$534K -29,343 -42%
AQR Capital Management
117
AQR Capital Management
Connecticut
$514K +$737K +40,506 New
Jane Street
118
Jane Street
New York
$508K -$11.2M -616,374 -94%
IFG
119
Independent Financial Group
California
$507K +$28.7K +1,578 +4%
Man Group
120
Man Group
United Kingdom
$498K +$711K +39,099 New
Raymond James Financial
121
Raymond James Financial
Florida
$480K +$55.9K +3,076 +9%
MSRPS
122
Maryland State Retirement & Pension System
Maryland
$471K +$673K +36,992 New
New York State Common Retirement Fund
123
New York State Common Retirement Fund
New York
$471K
AB
124
Amalgamated Bank
New York
$455K -$381K -20,978 -37%
TRSOTSOK
125
Teachers Retirement System of the State of Kentucky
Kentucky
$445K

ARWR Hedge Fund Activity: Q1 2025 in Review

265 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Arrowhead Research (ARWR) for Q1 2025, worth a combined $1.34B — down 28% from $1.88B a quarter earlier.

Sellers outnumbered buyers: 46 funds closed out of ARWR and 43 opened new positions — a net loss of 3 holders — while 82 trimmed existing stakes and 89 added.

The largest buyer was BlackRock, adding an estimated $68.2M. The largest seller was Fidelity Investments, cutting an estimated $32.5M.

  • 265 institutional investors held Arrowhead Research (ARWR) as of Q1 2025, down from 269 in Q4 2024.
  • Funds reported $1.34B of Arrowhead Research stock for Q1 2025, down 28% quarter-over-quarter.
  • 43 funds opened new Arrowhead Research positions in Q1 2025 and 46 closed out, a net change of -3 holders.
  • The largest Arrowhead Research buyer in Q1 2025 was BlackRock, an estimated $68.2M added.
  • The largest Arrowhead Research seller in Q1 2025 was Fidelity Investments, an estimated $32.5M sold.

Based on aggregated 13F filings for Q1 2025.