Comerica Bank
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Comerica Bank’s Arrowhead Research ARWR Stock Holding History

Comerica Bank’s Portfolio ARWR Stock Details ARWR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$2.07M Sell
31,183
-7,777
-20% -$381K 0.01% 1102
2025
Q3 		$1.34M Sell
38,960
-4,472
-10% -$98.3K 0.01% 1377
2025
Q2 		$686K Buy
43,432
+1,089
+3% +$15.6K ﹤0.01% 1722
2025
Q1 		$539K Buy
42,343
+6,422
+18% +$117K ﹤0.01% 1806
2024
Q4 		$675K Sell
35,921
-2,259
-6% -$46.5K ﹤0.01% 1753
2024
Q3 		$740K Sell
38,180
-6,092
-14% -$149K ﹤0.01% 1707
2024
Q2 		$1.15M Sell
44,272
-4,040
-8% -$99.3K ﹤0.01% 1408
2024
Q1 		$1.38M Buy
48,312
+4,855
+11% +$155K 0.01% 1359
2023
Q4 		$1.33M Sell
43,457
-51
-0.1% -$1.35K 0.01% 1384
2023
Q3 		$1.17M Buy
+43,508
New +$1.33M 0.01% 1354
2022
Q4 		$1.72M Sell
46,658
-845
-2% -$28K 0.01% 1165
2022
Q3 		$1.49M Sell
47,503
-755
-2% -$30.5K 0.01% 1241
2022
Q2 		$2.06M Sell
48,258
-75
-0.2% -$2.82K 0.02% 1080
2022
Q1 		$2.21M Buy
48,333
+2,281
+5% +$113K 0.02% 1097
2021
Q4 		$2.35M Sell
46,052
-1,230
-3% -$84.5K 0.02% 1050
2021
Q3 		$3.12M Sell
47,282
-9,475
-17% -$613K 0.02% 988
2021
Q2 		$3.31M Sell
56,757
-883
-2% -$65.7K 0.02% 977
2021
Q1 		$4.13M Sell
57,640
-2,491
-4% -$193K 0.02% 869
2020
Q4 		$4.93M Sell
60,131
-1,382
-2% -$88.4K 0.03% 709
2020
Q3 		$3.62M Sell
61,513
-460
-0.7% -$19.9K 0.03% 759
2020
Q2 		$3.01M Buy
61,973
+4,549
+8% +$161K 0.02% 807
2020
Q1 		$2.23M Buy
57,424
+12
+0% +$484 0.02% 854
2019
Q4 		$2.38M Sell
57,412
-31,822
-36% -$1.58M 0.02% 1014
2019
Q3 		$3.29M Buy
89,234
+627
+0.7% +$18.6K 0.03% 743
2019
Q2 		$2.53M Buy
+88,607
New +$1.94M 0.02% 941

Other funds holding ARWR

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
SPC
Slate Path Capital New York $7.22B AUM 110.75% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
Arrowstreet Capital
Arrowstreet Capital Boston, Massachusetts $225B AUM 49.49% 1-Year Est. Return
FAM
Fred Alger Management New York $30B AUM 76.99% 1-Year Est. Return

Comerica Bank's ARWR Position: Q4 2025 in Review

Comerica Bank reduced its Arrowhead Research (ARWR) stake by 20% in Q4 2025, selling an estimated $381K and leaving 31,183 shares worth $2.07M. The position accounts for 0.01% of the portfolio, ranked #1102.

Comerica Bank first reported a position in ARWR in Q2 2019 and has held it in 25 quarters since. The position peaked at $4.93M in Q4 2020. 401 funds tracked by Wall St. Rank hold ARWR as of Q4 2025.

  • Comerica Bank held 31,183 shares of Arrowhead Research worth $2.07M as of Q4 2025.
  • Comerica Bank sold 7,777 Arrowhead Research shares in Q4 2025, an estimated $381K.
  • Arrowhead Research made up 0.01% of Comerica Bank's portfolio in Q4 2025, its #1102 holding.
  • Comerica Bank first reported a position in Arrowhead Research in Q2 2019 and has held it in 25 quarters since.
  • Comerica Bank's Arrowhead Research position peaked at $4.93M in Q4 2020.
  • 401 funds tracked by Wall St. Rank held Arrowhead Research as of Q4 2025.

Based on Comerica Bank's 13F filing for Q4 2025, filed 29 Jan 2026.