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Arrowhead Research

265 hedge funds and large institutions have $1.34B invested in Arrowhead Research in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 89 increasing their positions, 82 reducing their positions, and 46 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 82

7% less first-time investments, than exits

New positions opened: 43 | Existing positions closed: 46

1% less funds holding

Funds holding: 269265 (-4)

3.44% less ownership

Funds ownership: 80.16%76.72% (-3.4%)

25% less call options, than puts

Call options by funds: $4.66M | Put options by funds: $6.24M

28% less capital invested

Capital invested by funds: $1.88B → $1.34B (-$532M)

Holders
265
Holders Change
-4
Holders Change %
-1.49%
% of All Funds
3.55%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
43
Increased
89
Reduced
82
Closed
46
Calls
$4.66M
Puts
$6.24M
Net Calls
-$1.58M
Net Calls Change
-$3.28M
Name Holding Trade Value Shares
Change
Change in
Stake
Principal Financial Group
26
Principal Financial Group
Iowa
$8.01M +$6.19M +340,191 +118%
WP
27
Woodline Partners
California
$7.16M -$5.05M -277,999 -33%
ACM
28
Aquilo Capital Management
California
$7.01M -$2.86M -157,459 -22%
JP Morgan Chase
29
JP Morgan Chase
New York
$6.21M -$27.9M -1,532,755 -76%
Fisher Asset Management
30
Fisher Asset Management
Washington
$6.16M +$6.19M +340,314 +238%
ClearBridge Investments
31
ClearBridge Investments
New York
$5.86M +$8.36M +459,854 New
Public Sector Pension Investment Board (PSP Investments)
32
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$5.09M +$7.27M +399,870 New
Legal & General Group
33
Legal & General Group
United Kingdom
$5.03M +$2.72M +149,842 +61%
RhumbLine Advisers
34
RhumbLine Advisers
Massachusetts
$4.41M -$625K -34,365 -9%
N
35
Nuveen
North Carolina
$4.3M +$93.3K +5,129 +2%
Citigroup
36
Citigroup
New York
$4.17M +$2.79M +153,402 +88%
Invesco
37
Invesco
Georgia
$4M +$2.51M +137,845 +78%
Pictet Asset Management
38
Pictet Asset Management
Switzerland
$3.97M +$4.98M +273,816 +1,926%
EP
39
Edgestream Partners
New Jersey
$3.89M +$3.37M +185,096 +154%
Susquehanna International Group
40
Susquehanna International Group
Pennsylvania
$3.69M -$2.34M -128,870 -31%
Ameriprise
41
Ameriprise
Minnesota
$3.65M +$1.11M +61,243 +27%
SAM
42
Silvercrest Asset Management
New York
$3.56M -$13.9K -762 -0.3%
SFM
43
Sphera Funds Management
Israel
$3.54M +$1.45M +80,000 +40%
Deutsche Bank
44
Deutsche Bank
Germany
$3.18M -$163K -8,975 -3%
JJ
45
Johnson & Johnson
New Jersey
$3.15M
Squarepoint
46
Squarepoint
New York
$3.06M +$2.8M +154,131 +179%
Mirae Asset Global ETFs Holdings
47
Mirae Asset Global ETFs Holdings
Hong Kong
$3.05M -$79.5K -4,374 -2%
Barclays
48
Barclays
United Kingdom
$2.93M -$1.5M -82,422 -26%
Swiss National Bank
49
Swiss National Bank
Switzerland
$2.76M -$56.4K -3,100 -1%
Hudson Bay Capital Management
50
Hudson Bay Capital Management
Connecticut
$2.72M +$693K +38,130 +22%

ARWR Hedge Fund Activity: Q1 2025 in Review

265 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Arrowhead Research (ARWR) for Q1 2025, worth a combined $1.34B — down 28% from $1.88B a quarter earlier.

Sellers outnumbered buyers: 46 funds closed out of ARWR and 43 opened new positions — a net loss of 3 holders — while 82 trimmed existing stakes and 89 added.

The largest buyer was BlackRock, adding an estimated $68.2M. The largest seller was Fidelity Investments, cutting an estimated $32.5M.

  • 265 institutional investors held Arrowhead Research (ARWR) as of Q1 2025, down from 269 in Q4 2024.
  • Funds reported $1.34B of Arrowhead Research stock for Q1 2025, down 28% quarter-over-quarter.
  • 43 funds opened new Arrowhead Research positions in Q1 2025 and 46 closed out, a net change of -3 holders.
  • The largest Arrowhead Research buyer in Q1 2025 was BlackRock, an estimated $68.2M added.
  • The largest Arrowhead Research seller in Q1 2025 was Fidelity Investments, an estimated $32.5M sold.

Based on aggregated 13F filings for Q1 2025.