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Amylyx Pharmaceuticals

167 hedge funds and large institutions have $1.49B invested in Amylyx Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 56 funds opening new positions, 44 increasing their positions, 48 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

31.41% more ownership

Funds ownership: 91.64%123.05% (+31%)

28% more funds holding

Funds holding: 130167 (+37)

8% less repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 48

Holders
167
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$7.31M
Puts
$2.15M
Net Calls
Net Calls Change

Top Sellers

1 -$27.2M
2 -$27M
3 -$23.7M
4
Millennium Management
Millennium Management
New York
-$14.9M
5
Citadel Advisors
Citadel Advisors
Florida
-$13.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Manulife (Manufacturers Life Insurance)
101
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$323K
PAP
102
Persistent Asset Partners
Hong Kong
$311K
New York State Common Retirement Fund
103
New York State Common Retirement Fund
New York
$298K
PCM
104
Parsons Capital Management
Rhode Island
$294K
VPIM
105
Vanguard Personalized Indexing Management
California
$287K
HSBC Holdings
106
HSBC Holdings
United Kingdom
$278K
PPWP
107
Premier Path Wealth Partners
New Jersey
$275K
Brown Advisory
108
Brown Advisory
Maryland
$271K
Renaissance Technologies
109
Renaissance Technologies
New York
$270K
IIM
110
INTECH Investment Management
Florida
$265K
PFSRSONJ
111
Police & Firemen's Retirement System of New Jersey
New Jersey
$262K
OAM
112
Oxford Asset Management
United Kingdom
$260K
EC
113
EntryPoint Capital
New York
$233K
QT
114
Quantbot Technologies
New York
$226K
CUAMC
115
China Universal Asset Management Company
China
$212K
ProShare Advisors
116
ProShare Advisors
Maryland
$204K
BNP Paribas Financial Markets
117
BNP Paribas Financial Markets
France
$199K
State of Wisconsin Investment Board
118
State of Wisconsin Investment Board
Wisconsin
$189K
A
119
AlphaQuest
New York
$185K
PA
120
Profund Advisors
Maryland
$182K
VOYA Investment Management
121
VOYA Investment Management
Georgia
$177K
SG Americas Securities
122
SG Americas Securities
New York
$161K
Capstone Investment Advisors
123
Capstone Investment Advisors
New York
$145K
LCM
124
Landscape Capital Management
New Jersey
$141K
Prudential Financial
125
Prudential Financial
New Jersey
$138K