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Amylyx Pharmaceuticals
AMLX

Overview Fund Activity

134 hedge funds and large institutions have $262M invested in Amylyx Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 50 increasing their positions, 31 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
134
Holders Change
+14
Holders Change %
+11.67%
% of All Funds
1.82%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.01%
New
32
Increased
50
Reduced
31
Closed
16
Calls
$524K
Puts
$606K
Net Calls
-$82K
Net Calls Change
+$497K

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$20.2M
2
Millennium Management
Millennium Management
New York
+$8.81M
3
GPP
Great Point Partners
Connecticut
+$6.41M
4
WP
Woodline Partners
California
+$5.7M
5
SVCM
Saturn V Capital Management
Texas
+$5.44M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$5.78M
2
Jane Street
Jane Street
New York
-$1.54M
3
CSS
Cubist Systematic Strategies
Connecticut
-$1.38M
4
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$1.31M
5
Walleye Capital
Walleye Capital
New York
-$948K
Name Holding Trade Value Shares
Change 		Shares
Change %
Balyasny Asset Management
51
Balyasny Asset Management
Illinois
$526K +$348K +98,311 +196%
Bank of Montreal
52
Bank of Montreal
Ontario, Canada
$508K – – –
Northern Trust
53
Northern Trust
Illinois
$493K +$116K +32,768 +31%
Barclays
54
Barclays
United Kingdom
$486K +$221K +62,560 +84%
HF
55
HRT Financial
New York
$453K +$453K +127,998 New
Dimensional Fund Advisors
56
Dimensional Fund Advisors
Texas
$438K +$246K +69,462 +128%
SSA
57
Schonfeld Strategic Advisors
New York
$415K -$272K -76,791 -40%
American Century Companies
58
American Century Companies
Missouri
$379K +$169K +47,704 +80%
TCM
59
Tang Capital Management
California
$354K – – –
CF
60
Cantor Fitzgerald
New York
$354K +$354K +100,000 New
Man Group
61
Man Group
United Kingdom
$309K -$45K -12,707 -13%
HWAM
62
Hennion & Walsh Asset Management
New Jersey
$295K -$26.1K -7,383 -8%
CSS
63
Cubist Systematic Strategies
Connecticut
$294K -$1.38M -389,267 -82%
Jacobs Levy Equity Management
64
Jacobs Levy Equity Management
New Jersey
$273K -$842K -237,848 -76%
Squarepoint
65
Squarepoint
New York
$269K +$2K +565 +0.8%
JG
66
Jain Global
New York
$262K +$262K +73,942 New
AA
67
ALPS Advisors
Colorado
$239K +$43.1K +12,167 +22%
ECM
68
ExodusPoint Capital Management
New York
$211K -$166K -46,746 -44%
T. Rowe Price Associates
69
T. Rowe Price Associates
Maryland
$205K – – –
AG
70
Algert Global
California
$202K +$202K +57,133 New
JPMorgan Chase & Co
71
JPMorgan Chase & Co
New York
$191K -$5.44K -1,537 -3%
Mariner
72
Mariner
Kansas
$180K +$1.3K +367 +0.7%
JFG
73
Jefferies Financial Group
New York
$164K – – –
Invesco
74
Invesco
Georgia
$162K +$162K +45,694 New
Group One Trading
75
Group One Trading
Illinois
$153K -$23.6K -6,665 -13%
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