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Amylyx Pharmaceuticals

122 hedge funds and large institutions have $188M invested in Amylyx Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 35 increasing their positions, 40 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

65% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 20

34% more capital invested

Capital invested by funds: $141M → $188M (+$47.6M)

11% more funds holding

Funds holding: 110122 (+12)

8.85% more ownership

Funds ownership: 63.82%72.67% (+8.8%)

13% less repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 40

30% less call options, than puts

Call options by funds: $1.36M | Put options by funds: $1.94M

Holders
122
Holders Change
+12
Holders Change %
+10.91%
% of All Funds
1.61%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
33
Increased
35
Reduced
40
Closed
20
Calls
$1.36M
Puts
$1.94M
Net Calls
-$579K
Net Calls Change
+$1.67M
Name Holding Trade Value Shares
Change
Change in
Stake
Geode Capital Management
26
Geode Capital Management
Massachusetts
$2.15M +$79.4K +16,864 +3%
Walleye Capital
27
Walleye Capital
New York
$1.96M -$714K -151,810 -23%
CSS
28
Cubist Systematic Strategies
Connecticut
$1.79M +$1.99M +423,316 +862%
Renaissance Technologies
29
Renaissance Technologies
New York
$1.76M +$906K +192,600 +71%
Morgan Stanley
30
Morgan Stanley
New York
$1.75M -$66.1K -14,045 -3%
O
31
OrbiMed
New York
$1.32M +$1.64M +348,000 New
Jacobs Levy Equity Management
32
Jacobs Levy Equity Management
New Jersey
$1.19M -$769K -163,501 -34%
D.E. Shaw & Co
33
D.E. Shaw & Co
New York
$1.16M -$1.81M -384,322 -56%
Charles Schwab
34
Charles Schwab
California
$1.13M -$15.6K -3,321 -1%
AC
35
Aldebaran Capital
Indiana
$993K -$33.2K -7,050 -3%
Two Sigma Advisers
36
Two Sigma Advisers
New York
$912K -$320K -68,100 -22%
State Street
37
State Street
Massachusetts
$825K +$299K +63,475 +41%
Wellington Management Group
38
Wellington Management Group
Massachusetts
$793K +$987K +209,708 New
Federated Hermes
39
Federated Hermes
Pennsylvania
$765K +$75.4K +16,030 +9%
IC
40
Ikarian Capital
Texas
$760K -$345K -73,364 -27%
SSA
41
Schonfeld Strategic Advisors
New York
$733K +$129K +27,502 +17%
AQR Capital Management
42
AQR Capital Management
Connecticut
$712K -$2.17M -460,693 -71%
Marshall Wace
43
Marshall Wace
United Kingdom
$698K -$467K -99,308 -35%
AWG
44
Alpha Wave Global
New York
$562K -$2.45M -520,860 -78%
BCM
45
Bridgeway Capital Management
Texas
$554K +$77.6K +16,500 +13%
Bank of Montreal
46
Bank of Montreal
Ontario, Canada
$542K
KCM
47
Kennondale Capital Management
Virginia
$508K +$633K +134,445 New
Mackenzie Financial
48
Mackenzie Financial
Ontario, Canada
$421K +$367K +78,070 +235%
Northern Trust
49
Northern Trust
Illinois
$403K +$52.8K +11,214 +12%
ECM
50
ExodusPoint Capital Management
New York
$402K +$500K +106,237 New

AMLX Hedge Fund Activity: Q4 2024 in Review

122 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Amylyx Pharmaceuticals (AMLX) for Q4 2024, worth a combined $188M — up 34% from $141M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new AMLX positions and 20 closed out — a net gain of 13 holders — while 35 added to existing stakes and 40 trimmed.

The largest buyer was Perceptive Advisors, adding an estimated $21.9M. The largest seller was Alyeska Investment Group, cutting an estimated $5.65M.

  • 122 institutional investors held Amylyx Pharmaceuticals (AMLX) as of Q4 2024, up from 110 in Q3 2024.
  • Funds reported $188M of Amylyx Pharmaceuticals stock for Q4 2024, up 34% quarter-over-quarter.
  • 33 funds opened new Amylyx Pharmaceuticals positions in Q4 2024 and 20 closed out, a net change of +13 holders.
  • The largest Amylyx Pharmaceuticals buyer in Q4 2024 was Perceptive Advisors, an estimated $21.9M added.
  • The largest Amylyx Pharmaceuticals seller in Q4 2024 was Alyeska Investment Group, an estimated $5.65M sold.

Based on aggregated 13F filings for Q4 2024.