Two Sigma Advisers
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Two Sigma Advisers’s Twist Bioscience TWST Stock Holding History

Two Sigma Advisers’s Portfolio TWST Stock Details TWST Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-31,400
Closed -$996K – 2015
2025
Q4 		$996K Buy
31,400
+5,400
+21% +$168K ﹤0.01% 1483
2025
Q3 		$732K Sell
26,000
-6,900
-21% -$209K ﹤0.01% 1607
2025
Q2 		$1.21M Buy
32,900
+800
+2% +$27.6K ﹤0.01% 1352
2025
Q1 		$1.26M Sell
32,100
-183,500
-85% -$8.26M ﹤0.01% 1363
2024
Q4 		$10M Sell
215,600
-64,900
-23% -$2.93M 0.02% 484
2024
Q3 		$12.7M Sell
280,500
-59,500
-18% -$2.83M 0.03% 425
2024
Q2 		$16.8M Buy
340,000
+252,700
+289% +$10.3M 0.04% 388
2024
Q1 		$3M Sell
87,300
-5,800
-6% -$209K 0.01% 1014
2023
Q4 		$3.43M Buy
93,100
+29,600
+47% +$684K 0.01% 993
2023
Q3 		$1.29M Sell
63,500
-13,400
-17% -$294K ﹤0.01% 1419
2023
Q2 		$1.57M Sell
76,900
-35,300
-31% -$529K ﹤0.01% 1324
2023
Q1 		$1.69M Buy
112,200
+96,500
+615% +$2.13M ﹤0.01% 1360
2022
Q4 		$374K Buy
15,700
+6,800
+76% +$197K ﹤0.01% 1996
2022
Q3 		$314K Sell
8,900
-3,800
-30% -$161K ﹤0.01% 2029
2022
Q2 		$444K Sell
12,700
-17,600
-58% -$623K ﹤0.01% 1975
2022
Q1 		$1.5M Buy
+30,300
New +$1.68M ﹤0.01% 1417
2021
Q4 		– Sell
-4,300
Closed -$460K – 2811
2021
Q3 		$460K Sell
4,300
-11,700
-73% -$1.34M ﹤0.01% 1957
2021
Q2 		$2.13M Sell
16,000
-30,900
-66% -$3.59M 0.01% 1273
2021
Q1 		$5.81M Buy
46,900
+30,600
+188% +$4.65M 0.02% 792
2020
Q4 		$2.3M Buy
16,300
+9,900
+155% +$1.1M 0.01% 1187
2020
Q3 		$486K Hold
6,400
– – ﹤0.01% 1832
2020
Q2 		$290K Sell
6,400
-7,000
-52% -$251K ﹤0.01% 2132
2020
Q1 		$410K Buy
+13,400
New +$360K ﹤0.01% 1881
2019
Q3 		– Sell
-16,800
Closed -$487K – 2393
2019
Q2 		$487K Buy
+16,800
New +$444K ﹤0.01% 1825

Other funds holding TWST

Artisan Partners
Artisan Partners Milwaukee, Wisconsin $63.1B AUM 35.51% 1-Year Est. Return
AIM
ARK Investment Management St. Petersburg, Florida $15.4B AUM 50.29% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
EIG
EdgePoint Investment Group Toronto, Ontario, Canada $13.2B AUM 32.43% 1-Year Est. Return
William Blair Investment Management
William Blair Investment Management Chicago, Illinois $33.3B AUM 44.76% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Invesco
Invesco Atlanta, Georgia $1.26T AUM 61.52% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Two Sigma Advisers's TWST Position: Q1 2026 in Review

Two Sigma Advisers sold out of Twist Bioscience (TWST) in Q1 2026, closing a stake of 31,400 shares — an estimated $996K sold.

Two Sigma Advisers first reported a position in TWST in Q2 2019 and held it in 24 quarters. The position peaked at $16.8M in Q2 2024. 281 funds tracked by Wall St. Rank hold TWST as of Q1 2026.

  • Two Sigma Advisers reported no remaining Twist Bioscience position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 31,400 Twist Bioscience shares in Q1 2026, an estimated $996K.
  • Two Sigma Advisers first reported a position in Twist Bioscience in Q2 2019 and held it in 24 quarters.
  • Two Sigma Advisers's Twist Bioscience position peaked at $16.8M in Q2 2024.
  • 281 funds tracked by Wall St. Rank held Twist Bioscience as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.